Etoposide EP Impurity J CAS 118356-05-1
| CAS No. | 118356-05-1 |
| Molecular Formula | C22H22O8 |
| Molecular Weight | 414.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 414.41 g/mol gives Etoposide EP Impurity J distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Etoposide EP Impurity J (CAS 118356-05-1), a pharmacopoeial impurity reference standard (molecular formula C22H22O8, MW 414.41 g/mol) used for the identification and quantification of trace impurities in APIs.
Etoposide EP Impurity J (C22H22O8) contains a flavonoid core, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H22O8 |
| Molecular Weight | 414.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
Related Etoposide Standards
- Etoposide EP Impurity M (CAS 518-28-5)
- Etoposide Impurity 25 (CAS CATO-C4X-202425)
- Etoposide Impurity 35 (CAS CATO-C4X-202435)
- Etoposide Impurity 38 (CAS CATO-C4X-202438)
- Etoposide Impurity 31 (CAS CATO-C4X-202431)
- Etoposide EP Impurity H (CAS 102306-95-6)
- Etoposide EP Impurity L (CAS 40505-27-9)
- Etoposide Impurity 29 (CAS CATO-C4X-202429)
Recommended Standards
- epi-Sancycline (CAS CATO-C4X-169949)
- Minocycline EP Impurity B (CAS 808-26-4)
- Venetola Impurity 19 (CAS CATO-C4X-249519)
- Sancycline (CAS CATO-C4X-169913)
- Amorolfine impurity 72 (CAS 59229-60-6)
- Flunarizine EP Impurity C HCl (CAS 90830-31-2(free base))
- Trospium EP Impurity C (CAS 3464-71-9)
- 3-Isopropyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine dihydrochloride (CAS 1269397-52-5)
- 2-((4-Chlorobenzyl)thio)-3-methylthieno[3,2-d]pyrimidin-4(3H)-one (CAS 339105-67-8)
- 4-(aminomethyl)-3-bromoaniline (CAS 624814-19-3)
- 1-((6-Chloroimidazo[1,2-a]pyridin-2-yl)methyl)pyrrolidin-3-amine (CAS 1272854-37-1)
- Gliotoxin (CAS 67-99-2)
- N-Fluoro-6-(trifluoromethyl)pyridinium-2-sulphonate (CAS 231285-89-5)
- D-[Asp]9-Semaglutide (CAS CATO-CPTD788631)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com