Etoposide Impurity 25 CAS CATO-C4X-202425
| CAS No. | CATO-C4X-202425 |
| Molecular Formula | C12H14Cl4O8 |
| Molecular Weight | 428.05 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 428.05 g/mol gives Etoposide Impurity 25 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Etoposide Impurity 25 (CAS CATO-C4X-202425), a pharmacopoeial impurity reference standard (molecular formula C12H14Cl4O8, MW 428.05 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, Etoposide Impurity 25 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 428.05 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H14Cl4O8 |
| Molecular Weight | 428.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Etoposide Standards
- Etoposide Impurity 35 (CAS CATO-C4X-202435)
- Etoposide Impurity 38 (CAS CATO-C4X-202438)
- Etoposide Impurity 31 (CAS CATO-C4X-202431)
- Etoposide EP Impurity H (CAS 102306-95-6)
- Etoposide EP Impurity J (CAS 118356-05-1)
- Etoposide EP Impurity M (CAS 518-28-5)
- Etoposide EP Impurity L (CAS 40505-27-9)
- Etoposide Impurity 29 (CAS CATO-C4X-202429)
Recommended Standards
- (4aR,6R,7R,8S,8aR)-6-Hydroxy-2-methylhexahydropyrano[3,2-d][1,3]dioxine-7,8-diyl bis(2,2-Dichloroacetate) (CAS 149403-65-6)
- 1,5-Diamino-2,6-dibromo-4,8-dihydroxyanthracene-9,10-dione (CAS 30787-41-8)
- 1,5-Diamino-2,3-dibromo-4,8-dihydroxyanthracene-9,10-dione (CAS 31626-19-4)
- (2E)-3-(3-Bromophenyl)-N-(3-iodophenyl)prop-2-enamide (CAS 882079-32-5)
- Folic Acid Hydrate EP Impurity B (CAS 35011-47-3)
- Cefminox Impurity 5 (CAS CATO-C4X-19265)
- Palbociclib Impurity 93 HCl (CAS CATO-C4X-1125203)
- 2-Methyl-6-((3-methylbutan-2-yl)carbamoyl)nicotinic acid (CAS 1155163-37-3)
- 5-Amino-1-(8-fluoroquinolin-4-yl)-1H-pyrazole-4-carbonitrile (CAS 1221411-06-8)
- Evandamine (CAS 100035-75-4)
- (3R)-3-amino-3-(4-ethoxyphenyl)propan-1-ol (CAS 1212977-90-6)
- Tizanidine Hydrochloride EP Impurity A (CAS 51322-69-1（free base）)
- 5-Phenylthiophen-2(3H)-one (CAS 939-09-3)
- Cholecystokinin Octapeptide (1-5) (desulfated) (CAS 121880-96-4)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com