Piroxicam Impurity 27 CAS 1184017-37-5
| CAS No. | 1184017-37-5 |
| Molecular Formula | C12H15NO6S |
| Molecular Weight | 301.32 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Piroxicam Impurity 27 (CAS 1184017-37-5, C12H15NO6S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C12H15NO6S, Piroxicam Impurity 27 contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 301.32 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H15NO6S |
| Molecular Weight | 301.32 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Piroxicam Standards
- Piroxicam EP Impurity L(Meloxicam EP Impurity F) (CAS 118854-48-1)
- Piroxicam Impurity 20 (CAS CATO-C4X-173320)
- Piroxicam Impurity 19 (CAS CATO-C4X-173319)
- Piroxicam EP Impurity B (CAS 65897-46-3)
- Piroxicam Impurity 14 (CAS CATO-C4X-173314)
- Piroxicam EP Impurity K(Meloxicam EP Impurity A) (CAS 24683-26-9)
- Piroxicam Impurity 15 (CAS 208051-67-6)
- Piroxicam EP Impurity F (CAS 76508-37-7)
Recommended Standards
- Faropenem Impurity 82 (CAS CATO-C4X-128982)
- Parathion-d10 (CAS 350820-04-1)
- Faropenem Impurity 50 (CAS CATO-C4X-128950)
- N-(3,5-Difluorophenyl)-1-phenylcyclopentane-1-carboxamide (CAS 1023484-29-8)
- Flumetasone Pivalate EP Impurity C (CAS 1926-94-9)
- Vonoprazan Impurity 213 (CAS CATO-C4X-1020213)
- Terlipressin Impurity 38 (CAS CATO-C4X-219338)
- 1-Amino-N-(2-methoxyethyl)cyclopropane-1-carboxamide (CAS 1499840-03-7)
- 2-Benzylisoindoline (CAS 35180-14-4)
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- 1-(5-Amino-2-(octyloxy)phenyl)ethan-1-one hydrochloride (CAS 13724-19-1)
- 1-[2-(2-chloro-6-fluorophenyl)cyclopropyl]ethan-1-one (CAS 1038300-47-8)
- 3-(4-Chlorobenzyl)thieno[2,3-d]pyrimidin-4(3H)-one (CAS 338777-24-5)
- Vasonatrin Peptide (VNP) trifluoroacetate salt (CAS 141676-35-9)
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