2-(4-Bromo-2-fluorophenyl)-6-methylpyridine CAS 1187168-20-2
| CAS No. | 1187168-20-2 |
| Molecular Formula | C12H9BrFN |
| Molecular Weight | 266.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-(4-Bromo-2-fluorophenyl)-6-methylpyridine (CAS 1187168-20-2), a certified reference material (molecular formula C12H9BrFN, MW 266.11 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/bromine substitution, 2-(4-Bromo-2-fluorophenyl)-6-methylpyridine is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 266.11 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H9BrFN |
| Molecular Weight | 266.11 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- N-(4-Bromo-2-hydroxyphenyl)methanesulfonamide (CAS 105295-63-4)
- 5-(4-Bromo-2-fluorophenyl)-2-methylpyridine (CAS 1187163-44-5)
- 2-(4-Bromo-2-fluorophenyl)-5-methylpyridine (CAS 1187163-97-8)
- 4-(4-Bromo-2-fluorophenyl)-2-methylpyridine (CAS 1187168-25-7)
- 2-(4-Bromo-2-fluorophenyl)-4-methylpyridine (CAS 1187168-33-7)
- 2-(4-Bromo-2-fluorophenyl)-3-methylpyridine (CAS 1187169-99-8)
- 4-Bromo-3-methoxybenzenesulfonamide (CAS 1206104-66-6)
- 4-Bromo-2-methoxybenzenesulfonamide (CAS 1206143-12-5)
Recommended Standards
- Brimonidine EP Impurity E (CAS 168329-48-4)
- tert-Butyl 2,6-dichloro-5-fluoronicotinate (CAS 932705-76-5)
- n2-(4-Bromophenyl)-1,3,5-triazine-2,4-diamine (CAS 72274-25-0)
- Ethyl 2-bromo-4-(hydroxymethyl)thiazole-5-carboxylate (CAS 1206908-29-3)
- 2-(1H-Indol-3-yl)-2-methylpropan-1-amine hydrochloride (CAS 942148-13-2)
- N-(2-fluorophenyl)-6-(1H-1,2,4-triazol-1-yl)nicotinamide (CAS 672951-19-8)
- Ethyl Benzoate (CAS 93-89-0)
- 8-(tert-Butyldimethylsilyloxy) 8-Hydroxy Efavirenz, Technical Grade (CAS 1027042-31-4)
- (s)-2-Amino-2-(3-(trifluoromethoxy)phenyl)ethan-1-ol (CAS 1213564-65-8)
- (R)-N-(1-(3-nitrophenyl)ethyl)acetamide (CAS 472976-05-9)
- Methyl 6-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)picolinate (CAS 1402004-07-2)
- (S)-1-(4-bromo-3-chlorophenyl)propan-1-amine (CAS 1270158-84-3)
- Diethyl iSopropylphosphoramidate (CAS 22685-19-4)
- Insulin Degludec impurity 4 (CAS CATO-C4X-21574)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com