4-(4-Bromo-2-fluorophenyl)-2-methylpyridine CAS 1187168-25-7
| CAS No. | 1187168-25-7 |
| Molecular Formula | C12H9BrFN |
| Molecular Weight | 266.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 4-(4-Bromo-2-fluorophenyl)-2-methylpyridine (CAS 1187168-25-7), a certified reference material (molecular formula C12H9BrFN, MW 266.11 g/mol) for analytical method development and quality control.
The molecular framework of 4-(4-Bromo-2-fluorophenyl)-2-methylpyridine (C12H9BrFN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H9BrFN |
| Molecular Weight | 266.11 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- N-(4-Bromo-2-hydroxyphenyl)methanesulfonamide (CAS 105295-63-4)
- 5-(4-Bromo-2-fluorophenyl)-2-methylpyridine (CAS 1187163-44-5)
- 2-(4-Bromo-2-fluorophenyl)-5-methylpyridine (CAS 1187163-97-8)
- 2-(4-Bromo-2-fluorophenyl)-6-methylpyridine (CAS 1187168-20-2)
- 2-(4-Bromo-2-fluorophenyl)-4-methylpyridine (CAS 1187168-33-7)
- 2-(4-Bromo-2-fluorophenyl)-3-methylpyridine (CAS 1187169-99-8)
- 4-Bromo-3-methoxybenzenesulfonamide (CAS 1206104-66-6)
- 4-Bromo-2-methoxybenzenesulfonamide (CAS 1206143-12-5)
Recommended Standards
- Brimonidine EP Impurity E (CAS 168329-48-4)
- Ethyl 2-bromo-4-(hydroxymethyl)thiazole-5-carboxylate (CAS 1206908-29-3)
- tert-Butyl 2,6-dichloro-5-fluoronicotinate (CAS 932705-76-5)
- 2-Bromo-4-methoxybenzenesulfonamide (CAS 1208076-86-1)
- 1-(Piperidin-3-yl)-3-propylurea (CAS 1042776-98-6)
- Methyl 3-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-5-methyl-4-isoxazolecarboxylate (CAS 303997-60-6)
- 1-(4-Fluorophenyl)-3-methyl-1h-pyrazolo[3,4-b]pyridine-5-carboxylic acid (CAS 926193-95-5)
- 2-(Dibromo(nitro)methyl)-3-methylpyridine (CAS 35624-43-2)
- 2-Phenylfuran-3,4-dicarboxylic acid (CAS 240116-46-5)
- Tert-butyl 4-(cyclohexanecarboxamido)piperidine-1-carboxylate (CAS 1233955-27-5)
- N-Methyl-2-(piperidin-4-yloxy)acetamide (CAS 912761-44-5)
- (E)-2-Phenyl-4-(thiophen-2-ylmethylene)oxazol-5(4H)-one (CAS 88991-45-1)
- tert-Butyl 4-(2,6-dichloropyrimidin-4-yl)piperazine-1-carboxylate (CAS 1155306-28-7)
- Amyloid Precursor Frameshift Mutant C-Terminal Peptide trifluoroacetate salt (CAS 189125-14-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com