Hydroxyzine-d8DISCONTINUED CAS 1189480-47-4
| CAS No. | 1189480-47-4 |
| Molecular Formula | - |
| Molecular Weight | 382.95 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies Hydroxyzine-d8DISCONTINUED (CAS 1189480-47-4), a certified reference material (molecular formula C21H19D8ClN2O2, MW 382.95 g/mol) for analytical method development and quality control.
The molecular framework of Hydroxyzine-d8DISCONTINUED (C21H19D8ClN2O2) is characterized by deuterium isotope labeling, a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Hydroxyzine-d8DISCONTINUED meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H19D8ClN2O2 |
| Molecular Weight | 382.95 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Hydroxyzine Standards
- Hydroxyzine Impurity 2 (CAS CATO-C4X-16602)
- Hydroxyzine Impurity 5 (CAS 2469273-48-9)
- Hydroxyzine (CAS 68-88-2)
- Hydroxyzine Impurity B Hydrochloride salt (CAS 1263283-80-2)
- Hydroxyzine Impurity 4 (CAS CATO-C4X-16604)
- Hydroxyzine Impurity 1 (CAS 628-89-7)
- Hydroxyzine Pamoate (CAS 10246-75-0)
- Hydroxyzine Impurity 9 (CAS 1031-92-1)
Recommended Standards
- 5-chloro-N-[2-[2,3-dimethyl-4-[2-(1,1,2,2,2-pentadeuterioethoxy)ethyl]phenoxy]ethyl]-6-ethylpyrimidin-4-amine (CAS 1794979-20-6)
- 6,7-Dibromo-8-nitro-2,3-dihydrobenzo-[b][1,4]dioxine-5-carboxylic acid (CAS 66411-18-5)
- (E)-1-(4-(3-chlorophenyl)piperazin-1-yl)-3-(4-isobutylphenyl)prop-2-en-1-one (CAS 329778-14-5)
- Cl-C6-PEG4-C3-COOH (CAS 2127391-58-4)
- (R)-3-Bromo-2-methylpropanoic acid (CAS 89361-97-7)
- Tert-butyl (R)-3-((2-methoxyphenethyl)amino)pyrrolidine-1-carboxylate (CAS 947304-23-6)
- Methyl 3-formylbenzo[d]pyrrolo[2,1-b]thiazole-1-carboxylate (CAS 136427-69-5)
- 2-(3-((3-(Benzyloxy)-3-oxopropyl)amino)pyrrolidin-1-yl)acetic acid (CAS 1353957-62-6)
- Budesonide Impurity N2 (CAS 39672-76-9)
- 6-Amino-4-(trifluoromethyl)picolinonitrile (CAS 1807004-79-0)
- 2-((3,4-Dihydroquinoxalin-1(2H)-yl)methylene)malononitrile (CAS 6687-88-3)
- 8-oxatricyclo[7.4.0.0^{2,7}]trideca-1(9),2,4,6,10,12-hexaene-6-carbaldehyde 96706-46-6 (CAS 96706-46-6)
- (4Z)-3-Methyl-4-undecene (CAS 74645-87-7)
- DAPK Substrate Peptide (CAS 386769-53-5)
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