Ezetimibe Impurity 13(Open Ring Impurity) CAS 1197811-72-5

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.1197811-72-5
Molecular FormulaC24H23F2NO3
Molecular Weight411.44 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Ezetimibe Impurity 13(Open Ring Impurity) CAS 1197811-72-5 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 411.44 g/mol gives Ezetimibe Impurity 13(Open Ring Impurity) distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Ezetimibe Impurity 13(Open Ring Impurity) (CAS 1197811-72-5) is a certified pharmaceutical impurity reference standard with the molecular formula C24H23F2NO3 and a molecular weight of 411.44 g/mol.

Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Ezetimibe Impurity 13(Open Ring Impurity) is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 411.44 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures Ezetimibe Impurity 13(Open Ring Impurity) under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC24H23F2NO3
Molecular Weight411.44 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity>95%
StorageStore at room temperature, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)13.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Halogen ContentF-containing
Nitrogen Atoms1

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