Tretinoin EP Impurity G CAS 13100-69-1
| CAS No. | 13100-69-1 |
| Molecular Formula | C20H28O3 |
| Molecular Weight | 316.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Tretinoin EP Impurity G (CAS 13100-69-1), a pharmacopoeial impurity reference standard (molecular formula C20H28O3, MW 316.43 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Tretinoin EP Impurity G (C20H28O3) is characterized by a steroid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Tretinoin EP Impurity G under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H28O3 |
| Molecular Weight | 316.43 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1960 |
Related Tretinoin Standards
- 4-Oxo Tretinoin (4-Oxo Retinoic Acid) (CAS 38030-57-8)
- Tretinoin-d5 (CAS CATO-C4X-196937)
- Tretinoin Impurity 12 (CAS 3899-20-5)
- Tretinoin EP Impurity F (4-Methoxy Retinoic Acid) (CAS 81121-20-2)
- Tretinoin EP Impurity B (9,13-di-cis-Retinoic Acid) (CAS 5352-74-9)
- Tretinoin Impurity 27 (CAS CATO-C4X-196927)
- Tretinoin EP Impurity C (Isotretinoin EP Impurity C, 11,13-di-cis-Retinoic Acid) (CAS 3555-80-4)
- Tretinoin Impurity 7 (CAS 173326-85-7)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com