Chlorpheniramine Impurity 19 CAS CATO-C4X-118819
| CAS No. | CATO-C4X-118819 |
| Molecular Formula | C16H19ClN2 |
| Molecular Weight | 274.79 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, Chlorpheniramine Impurity 19 is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 274.79 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Chlorpheniramine Impurity 19 (CAS CATO-C4X-118819, C16H19ClN2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Chlorpheniramine Impurity 19 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H19ClN2 |
| Molecular Weight | 274.79 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorpheniramine Standards
- Chlorpheniramine Impurity 36 (CAS CATO-C4X-118836)
- Chlorpheniramine Impurity 38 (CAS CATO-C4X-118838)
- Chlorpheniramine Impurity 41 (CAS 101286-08-2)
- Chlorpheniramine (CAS 132-22-9)
- Chlorpheniramine-d6 (CAS 1185054-60-7)
- Chlorpheniramine Impurity 14 (CAS CATO-C4X-118814)
- R-Chlorpheniramine N-Oxide (CAS 142494-45-9)
- Chlorpheniramine Impurity 15 (CAS 120244-82-8)
Recommended Standards
- tert-butyl 7-chloro-3,4-dihydro-2H-1,8-naphthyridine-1-carboxylate (CAS 679392-23-5)
- tert-butyl 6-(chloromethyl)-1,3-dihydropyrrolo[3,4-c]pyridine-2-carboxylate (CAS 2222756-66-1)
- S-(2-(4-Chlorophenyl)-2-oxoethyl) O-ethyl carbonodithioate, 97% (CAS 91193-23-6)
- Dexchlorpheniramine EP Impurity B (CAS 32188-09-3)
- Dotinurad Impurity 71 (CAS CATO-C4X-249471)
- Apalutamide Impurity 69 (CAS CATO-C4X-274969)
- Lacosamide Impurity 17 (CAS CATO-C4X-183017)
- N-(4-Chlorophenyl)piperidine-3-carboxamide hydrochloride (CAS 599184-20-0)
- 2-chloro-1-(2-chloro-4-methoxyphenyl)ethan-1-one (CAS 51488-82-5)
- 2-(Isopentylthio)benzoyl chloride (CAS 91767-36-1)
- (4R,5S)-2-(5-Fluoropyridin-2-yl)-4,5-diphenyl-4,5-dihydrooxazole (CAS 2757083-58-0)
- n-(5-Nitro-1,3-dioxo-1,3-dihydroisobenzofuran-4-yl)acetamide (CAS 209324-66-3)
- Methyl 1-[(4-methylphenyl)methyl]-1H-indole-2-carboxylate (CAS 860611-68-3)
- SAMS Peptide (CAS 125911-68-4)
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