Beclometasone Dipropionate EP Impurity N CAS 1204582-47-7

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.1204582-47-7
Molecular FormulaC28H36BrClO7
Molecular Weight599.94 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Beclometasone Dipropionate EP Impurity N CAS 1204582-47-7 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 599.94 g/mol gives Beclometasone Dipropionate EP Impurity N distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Beclometasone Dipropionate EP Impurity N (CAS 1204582-47-7), a pharmacopoeial impurity reference standard (molecular formula C28H36BrClO7, MW 599.94 g/mol) used for the identification and quantification of trace impurities in APIs.

Structurally, Beclometasone Dipropionate EP Impurity N (C28H36BrClO7) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/bromine substitution, a polycyclic aromatic system. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 599.94 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC28H36BrClO7
Molecular Weight599.94 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity>95%
StorageStore at room temperature, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Halogen ContentCl/Br-containing

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