Beclometasone Dipropionate Monohydrate EP Impurity L CAS 114371-33-4
| CAS No. | 114371-33-4 |
| Molecular Formula | C28H39ClO7 |
| Molecular Weight | 523.06 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Beclometasone Dipropionate Monohydrate EP Impurity L (CAS 114371-33-4) is a certified pharmaceutical impurity reference standard with the molecular formula C28H39ClO7 and a molecular weight of 523.06 g/mol.
Beclometasone Dipropionate Monohydrate EP Impurity L (C28H39ClO7) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), Beclometasone Dipropionate Monohydrate EP Impurity L meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C28H39ClO7 |
| Molecular Weight | 523.06 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
Related Beclometasone Standards
- Beclometasone Dipropionate EP Impurity M (CAS 3100114-15-3)
- Beclometasone Impurity 52 (CAS CATO-C4X-147452)
- Beclometasone Dipropionate Monohydrate EP Impurity C (CAS CATO-C4X-14743)
- Beclometasone dipropionate EP Impurity B (CAS 5534-08-7)
- Beclometasone Dipropionate Monohydrate EP Impurity O (CAS 14527-61-8)
- Beclometasone Impurity 51 (CAS CATO-C4X-147451)
- Beclometasone Dipropionate Monohydrate EP Impurity E (CAS 887130-68-9)
- Beclometasone Impurity 43 (CAS CATO-C4X-147443)
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