Beclometasone Dipropionate Monohydrate EP Impurity F CAS 887130-69-0

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.887130-69-0
Molecular FormulaC28H36BrClO7
Molecular Weight599.94 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Beclometasone Dipropionate Monohydrate EP Impurity F CAS 887130-69-0 chemical structure

Description

The occurrence of Beclometasone Dipropionate Monohydrate EP Impurity F is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/bromine substitution, a polycyclic aromatic system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

Beclometasone Dipropionate Monohydrate EP Impurity F (CAS 887130-69-0) is a certified pharmaceutical impurity reference standard with the molecular formula C28H36BrClO7 and a molecular weight of 599.94 g/mol.

Structurally, Beclometasone Dipropionate Monohydrate EP Impurity F (C28H36BrClO7) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/bromine substitution, a polycyclic aromatic system. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 599.94 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC28H36BrClO7
Molecular Weight599.94 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity>95%
StorageStore at room temperature, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentCl/Br-containing

Related Beclometasone Standards

Recommended Standards

Why CATO?