Montelukast Impurity 26 CAS 120578-03-2
| CAS No. | 120578-03-2 |
| Molecular Formula | C18H12ClNO |
| Molecular Weight | 293.75 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Montelukast Impurity 26.
As a process- or degradation-related impurity, Montelukast Impurity 26 (CAS 120578-03-2, C18H12ClNO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C18H12ClNO, Montelukast Impurity 26 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 293.75 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Montelukast Impurity 26 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H12ClNO |
| Molecular Weight | 293.75 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Montelukast Standards
- Montelukast Impurity 44 (CAS 115104-40-0)
- Montelukast Disulfide Impurity (CAS 162515-67-5)
- Montelukast Impurity 42 (CAS 149968-10-5)
- Montelukast Impurity N27 (CAS 610-97-9)
- Montelukast Impurity 9 (CAS 30430-40-1)
- Montelukast Impurity 57 (CAS 30220-25-8)
- Montelukast Impurity N4 (CAS 855473-50-6)
- Montelukast Impurity 55 (CAS 152922-86-6)
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- Monosulfuron (CAS 155860-63-2)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com