N-[2-chloro-5-(trifluoromethyl)phenyl]-N'-[[2-(4-morpholinyl)-3-pyridinyl]methyl]-Urea CAS 1211298-93-9
| CAS No. | 1211298-93-9 |
| Molecular Formula | C18H18ClF3N4O2 |
| Molecular Weight | 414.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 414.81 g/mol gives N-[2-chloro-5-(trifluoromethyl)phenyl]-N'-[[2-(4-morpholinyl)-3-pyridinyl]methyl]-Urea distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
N-[2-chloro-5-(trifluoromethyl)phenyl]-N'-[[2-(4-morpholinyl)-3-pyridinyl]methyl]-Urea (CAS 1211298-93-9), molecular formula C18H18ClF3N4O2 and molecular weight 414.81 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, N-[2-chloro-5-(trifluoromethyl)phenyl]-N'-[[2-(4-morpholinyl)-3-pyridinyl]methyl]-Urea is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 414.81 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H18ClF3N4O2 |
| Molecular Weight | 414.81 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related N Standards
- N-(3-Chloro-4-methoxyphenyl)-1-[6-(trifluoromethyl)pyrimidin-4-yl]piperidine-4-carboxamide (CAS 1775546-35-4)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperidin-4-yl 4-methoxybenzoate (CAS 306976-41-0)
- Ethyl 2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-2-{[(4-methylphenyl)methyl]carbamoyl}acetate (CAS 478063-73-9)
- 2-(N-((4-Chloro-6-methoxypyrimidin-2-yl)carbamoyl)sulfamoyl)ethyl benzoate (CAS 94365-91-0)
- 4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-9-hydroxy-3,5-dioxo-4-azatricyclo[5.2.1.0^{2,6}]decane-8-carbonitrile (CAS 1005068-81-4)
- 1-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-6-[(2E)-2-(methoxyimino)ethyl]-4-oxo-1,4-dihydropyrimidine-5-carbonitrile (CAS 303148-49-4)
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Recommended Standards
- 3-Chlorosulfonyl-4-(2-methoxy-phenyl)-5-trifluoro-methyl-thiophene-2-carboxylic acid methyl ester (CAS 1431555-14-4)
- Methotrexate Impurity 71 (CAS CATO-C4X-115471)
- (3E)-1-[(2-Chlorophenyl)methyl]-3-{[3-(trifluoromethyl)phenyl]imino}-2,3-dihydro-1H-indol-2-one (CAS 478031-73-1)
- Methotrexate Impurity 69 (CAS CATO-C4X-115469)
- 97458-44-1 1,3-Diethyl-9H-thioxanthen-9-one MFCD02089377 (CAS 97458-44-1)
- 1-Benzyl 3-ethyl (3R,4R)-4-hydroxypyrrolidine-1,3-dicarboxylate (CAS 1373613-98-9)
- (S)-2-Amino-1-((R)-3-(benzyl(ethyl)amino)piperidin-1-yl)propan-1-one (CAS 1401666-85-0)
- 8-Amino-2-methyl-2H-benzo[b][1,4]oxazin-3(4H)-one (CAS 870064-81-6)
- 2-(4-Fluorophenyl)-6-hydroxy-4H-chromen-4-one (CAS 140439-37-8)
- 5,5'-(Hydroxyphosphoryl)diisophthalic acid (CAS 315664-57-4)
- 2-(4-Chlorophenyl)-2-oxoethyl 2-acetamido-2-[(4-methoxyphenyl)carbamoyl]acetate (CAS 551920-98-0)
- 2-(2-Bromoethyl)-1-fluoro-4-(trifluoromethyl)benzene (CAS 1260795-22-9)
- 4-Methoxy-6-methyl-5-nitro-2-(trifluoromethyl)-quinoline (CAS 175203-62-0)
- Des-Trp25-Tirzepatide (CAS CATO-CPTD788948)
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