N-(3-Chloro-4-methoxyphenyl)-1-[6-(trifluoromethyl)pyrimidin-4-yl]piperidine-4-carboxamide CAS 1775546-35-4
| CAS No. | 1775546-35-4 |
| Molecular Formula | C18H18ClF3N4O2 |
| Molecular Weight | 414.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C18H18ClF3N4O2, N-(3-Chloro-4-methoxyphenyl)-1-[6-(trifluoromethyl)pyrimidin-4-yl]piperidine-4-carboxamide contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 414.81 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies N-(3-Chloro-4-methoxyphenyl)-1-[6-(trifluoromethyl)pyrimidin-4-yl]piperidine-4-carboxamide (CAS 1775546-35-4), a certified reference material (molecular formula C18H18ClF3N4O2, MW 414.81 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H18ClF3N4O2 |
| Molecular Weight | 414.81 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related N Standards
- N-[2-chloro-5-(trifluoromethyl)phenyl]-N'-[[2-(4-morpholinyl)-3-pyridinyl]methyl]-Urea (CAS 1211298-93-9)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperidin-4-yl 4-methoxybenzoate (CAS 306976-41-0)
- Ethyl 2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-2-{[(4-methylphenyl)methyl]carbamoyl}acetate (CAS 478063-73-9)
- 2-(N-((4-Chloro-6-methoxypyrimidin-2-yl)carbamoyl)sulfamoyl)ethyl benzoate (CAS 94365-91-0)
- 4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-9-hydroxy-3,5-dioxo-4-azatricyclo[5.2.1.0^{2,6}]decane-8-carbonitrile (CAS 1005068-81-4)
- 1-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-6-[(2E)-2-(methoxyimino)ethyl]-4-oxo-1,4-dihydropyrimidine-5-carbonitrile (CAS 303148-49-4)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-4-(2,4-dimethoxyphenyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS 861206-40-8)
- 2-Chloro-N-(2-((2-cyano-4-nitrophenyl)diazenyl)-5-(diethylamino)phenyl)acetamide (CAS 64294-88-8)
Recommended Standards
- (3E)-1-[(2-Chlorophenyl)methyl]-3-{[3-(trifluoromethyl)phenyl]imino}-2,3-dihydro-1H-indol-2-one (CAS 478031-73-1)
- 3-Chlorosulfonyl-4-(2-methoxy-phenyl)-5-trifluoro-methyl-thiophene-2-carboxylic acid methyl ester (CAS 1431555-14-4)
- Methotrexate Impurity 71 (CAS CATO-C4X-115471)
- Methotrexate Impurity 69 (CAS CATO-C4X-115469)
- (4-tert-Butylphenyl)-methanesulfonamide (CAS 64732-37-2)
- 5-Chloro-2-(trifluoromethyl)-1H-benzo[d]imidazole (CAS 656-49-5)
- 6-((4-Chlorobenzyl)oxy)-2-azaspiro[3.3]heptane (CAS 1708160-24-0)
- 4-Iodo-1,2-dimethyl-1H-imidazole (CAS 343569-02-8)
- Pentan-1-amine hydrobromide (CAS 7334-94-3)
- 9-Fluoro-6-methyl-1,2,3,4-tetrahydrobenzo[b][1,6]naphthyridin-10(5H)-one (CAS 1355175-23-3)
- N1-(3-bromo-6-morpholino-4-(trifluoromethyl)pyridin-2-yl)ethane-1,2-diamine (CAS 1089330-42-6)
- 1-(1,3-Dimethyl-1h-pyrazol-4-yl)ethan-1-amine (CAS 911788-36-8)
- N-isobutylquinolin-5-amine (CAS 343953-24-2)
- [Ser]8-Acetylated Semaglutide (CAS CATO-C4X-2226218)
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