Amiodarone-D4 Hydrochloride CAS 1216715-80-8
| CAS No. | 1216715-80-8 |
| Molecular Formula | - |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Amiodarone-D4 Hydrochloride.
Amiodarone-D4 Hydrochloride (CAS 1216715-80-8) is a high-purity analytical reference standard with the molecular formula C25H25D4I2NO3HCl and a molecular weight of 685.79 g/mol.
The molecular framework of Amiodarone-D4 Hydrochloride (C25H25D4I2NO3HCl) is characterized by deuterium isotope labeling, a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C25H25D4I2NO3 HCl |
| Molecular Weight | 685.79 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl/I-containing |
| Nitrogen Atoms | 1 |
Related Amiodarone Standards
- Amiodarone EP Impurity H (CAS 100-35-6)
- Amiodarone EP Impurity G (CAS 1087223-70-8)
- Amiodarone EP Impurity B D4 HCl (CAS 1189960-80-2)
- Amiodarone D4 (CAS 1217169-60-2)
- Amiodarone Impurity 32 (CAS 134-92-9)
- Amiodarone Impurity 19 (CAS 1346604-30-5)
- Amiodarone Impurity 38 (CAS 138320-26-0)
- Amiodarone Impurity 39 (CAS 138320-27-1)
Recommended Standards
- 8-(Bromomethyl)isoquinoline hydrobromide (CAS 1215541-16-4)
- tert-Butyl (R)-2-(2,2,2-trifluoroethyl)piperazine-1-carboxylate (CAS 1240586-07-5)
- 5-Amino-2-nitrobenzenesulfonic acid (CAS 551-91-7)
- DL-2-Bromoamphetamine hydrochloride (CAS 861006-36-2)
- 1-Isopropyl-4-methyl-2-(vinyloxy)cyclohexane (CAS 46173-76-6)
- 4-Cyano-N,N-dimethyl-1H-pyrazole-1-sulfonamide (CAS 131661-50-2)
- Erlotinib Impurity 107 (CAS 299912-59-7)
- 1-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)ethan-1-amine dihydrochloride (CAS 1269152-37-5)
- 3-(Pyridin-3-yl)benzonitrile (CAS 4350-54-3)
- Liraglutide Impurity 19 TFA Salt (CAS CATO-C4X-199219)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com