Erlotinib Impurity 107 CAS 299912-59-7
| CAS No. | 299912-59-7 |
| Molecular Formula | C25H29N3O5 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Erlotinib Impurity 107.
CATO supplies Erlotinib Impurity 107 (CAS 299912-59-7), a pharmacopoeial impurity reference standard (molecular formula C25H29N3O5HCl, MW 487.98 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Erlotinib Impurity 107 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 487.98 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Erlotinib Impurity 107 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H29N3O5 HCl |
| Molecular Weight | 487.98 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Erlotinib Standards
- Erlotinib Impurity 97 (CAS 1012057-39-4)
- Erlotinib Impurity 93 (CAS 1058132-82-3)
- Erlotinib impurity 136 (CAS 1058651-74-3)
- Erlotinib D4 (CAS 1130852-41-3)
- Erlotinib Impurity 123 (CAS 1145671-36-8)
- Erlotinib Hydrochloride Impurity 3 (CAS 1145671-52-8)
- Erlotinib Impurity 51 (CAS 115665-66-2)
- Erlotinib-d6 HCl (CAS 1189953-78-3)
Recommended Standards
- Linezolid Impurity 61 (CAS CATO-C4X-107361)
- Amlodipine Impurity N1 (CAS 194472-27-0)
- Dinoprost Trometamol EP Impurity D (CAS 38432-87-0)
- 4-Chloro-3-iodo-6-methoxyquinoline (CAS 1190972-42-9)
- 1-(2,6-Difluoro-4-iodophenyl)-2,2,2-trifluoroethan-1-one (CAS 1208076-04-3)
- 2-(5-chloro-1H-indol-1-yl)ethan-1-amine (CAS 169674-88-8)
- 2-Benzyl-4-chloro-5-methoxypyridazin-3(2H)-one (CAS 40890-47-9)
- 3-(Dimethylamino)-4-hydroxybenzoic acid (CAS 892878-64-7)
- CAS 71479-88-4 (CAS 71479-88-4)
- Semaglutide impurity 256 (CAS CATO-C4X-2226256)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com