Anastrozole EP Impurity B CAS 1216898-82-6

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.1216898-82-6
Molecular FormulaC30H31N9
Molecular Weight517.63 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Anastrozole EP Impurity B CAS 1216898-82-6 chemical structure

Description

As a certified reference material (CRM), Anastrozole EP Impurity B meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Anastrozole EP Impurity B (CAS 1216898-82-6) is a certified pharmaceutical impurity reference standard with the molecular formula C30H31N9 and a molecular weight of 517.63 g/mol.

The molecular framework of Anastrozole EP Impurity B (C30H31N9) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

Physical & Chemical Properties

Molecular FormulaC30H31N9
Molecular Weight517.63 g/mol
AppearancePale yellow to yellow crystalline powder
Purity>95%
StorageStore at room temperature, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)20.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Nitrogen Atoms9

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