Anastrozole Impurity 34 CAS CATO-C4X-123934
| CAS No. | CATO-C4X-123934 |
| Molecular Formula | C15H15Br3N2 |
| Molecular Weight | 463.01 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Anastrozole Impurity 34 (CAS CATO-C4X-123934, C15H15Br3N2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C15H15Br3N2, Anastrozole Impurity 34 contains a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 463.01 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H15Br3N2 |
| Molecular Weight | 463.01 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Anastrozole Standards
- Anastrozole Impurity 33 (CAS CATO-C4X-123933)
- Anastrozole EP Impurity B (CAS 1216898-82-6)
- Anastrozole-d (CAS 1329809-14-4)
- Anastrozole EP Impurity D (CAS 1027160-12-8)
- Anastrozole Impurity 19 (CAS 918312-71-7)
- Anastrozole Impurity 21 (CAS CATO-C4X-123921)
- Anastrozole Impurity N2 (CAS 1186102-55-5)
- Anastrozole Impurity 37 (CAS CATO-C4X-123937)
Recommended Standards
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