(2-Fluoro-[1,1'-biphenyl]-3-yl)boronic acid CAS 1218790-57-8

Purity 97%+In StockPharmaceutical Standards
CAS No.1218790-57-8
Molecular FormulaC12H10BFO2
Molecular Weight216.02 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(2-Fluoro-[1,1'-biphenyl]-3-yl)boronic acid CAS 1218790-57-8 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 216.02 g/mol gives (2-Fluoro-[1,1'-biphenyl]-3-yl)boronic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies (2-Fluoro-[1,1'-biphenyl]-3-yl)boronic acid (CAS 1218790-57-8), a certified reference material (molecular formula C12H10BFO2, MW 216.02 g/mol) for analytical method development and quality control.

Structurally, (2-Fluoro-[1,1'-biphenyl]-3-yl)boronic acid (C12H10BFO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 7.5, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 216.02 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (2-Fluoro-[1,1'-biphenyl]-3-yl)boronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H10BFO2
Molecular Weight216.02 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)7.5
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Halogen ContentF-containing

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