2-Fluoro-4-biphenylylboronic acid CAS 178305-99-2
| CAS No. | 178305-99-2 |
| Molecular Formula | C12H10BFO2 |
| Molecular Weight | 216.02 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-Fluoro-4-biphenylylboronic acid (CAS 178305-99-2), molecular formula C12H10BFO2 and molecular weight 216.02 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Fluoro-4-biphenylylboronic acid (C12H10BFO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures 2-Fluoro-4-biphenylylboronic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H10BFO2 |
| Molecular Weight | 216.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | F-containing |
Related Fluoro Standards
- (4-Fluoro-[1,1'-biphenyl]-3-yl)boronic acid (CAS 1199616-73-3)
- (2-Fluoro-[1,1'-biphenyl]-3-yl)boronic acid (CAS 1218790-57-8)
- (2'-Fluoro-[1,1'-biphenyl]-4-yl)boronic acid (CAS 1383531-49-4)
- 2-Fluoro-biphenyl-5-ylboronic acid (CAS 1383532-12-4)
- (4'-Fluoro-[1,1'-biphenyl]-3-yl)boronic acid (CAS 159020-61-8)
- (4'-Fluoro-[1,1'-biphenyl]-2-yl)boronic acid (CAS 179526-94-4)
- (4-Fluoro-[1,1'-biphenyl]-2-yl)boronic acid (CAS 2243975-77-9)
- 3-Fluoro-4-biphenylboronic acid (CAS 409108-13-0)
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- 81988-89-8 UH11FDQ454 Ramoplanin A(sub 3) Ramoplanin A3 (S)-2-(3-Chloro-4-hydroxyphenyl)-N-(N(sup 2)-((2Z,4Z)-8-methyl-2,4-nonadienoyl)-(S)-asparaginyl-(2S,3S)-3-hydroxyasparaginyl-(R)-2-(p-hydroxyphenyl)glycyl-(R)-ornithyl-(2R,3R)-allothreonyl-2-(p-hydroxyphenyl)glycyl-2-(p-hydroxyphenyl)glycyl-(2S,3S)-allothreonyl-(S)-phenylalanyl-(R)-ornithyl-(S)-2-(p-((2-O-alpha-D-mannopyranosyl-alpha-D-mannopyranosyl)oxy)phenyl)glycyl-(2R,3R)-allothreonyl-(S)-2-(p-hydroxyphenyl)glycylglycyl-(S)-leucyl-(R)-alanyl)glycine psi1-lactone Ramoplanin A 1 (peptide moiety), 1-(N(sup 2)-methyl-1-oxo-2,4-nonadienyl)-L-asparagine)-11-(L-2-(4-((2-O-alpha-D-mannopyranosyl-alpha-D-mannopyranosyl)oxy)phenyl)glycine)-, (Z,Z)- UNII-UH11FDQ454 (CAS 81988-89-8)
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