(4-Fluoro-[1,1'-biphenyl]-2-yl)boronic acid CAS 2243975-77-9
| CAS No. | 2243975-77-9 |
| Molecular Formula | C12H10BFO2 |
| Molecular Weight | 216.02 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, (4-Fluoro-[1,1'-biphenyl]-2-yl)boronic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 216.02 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
(4-Fluoro-[1,1'-biphenyl]-2-yl)boronic acid (CAS 2243975-77-9) is a high-purity analytical reference standard with the molecular formula C12H10BFO2 and a molecular weight of 216.02 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H10BFO2 |
| Molecular Weight | 216.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
Related Fluoro Standards
- (4-Fluoro-[1,1'-biphenyl]-3-yl)boronic acid (CAS 1199616-73-3)
- (2-Fluoro-[1,1'-biphenyl]-3-yl)boronic acid (CAS 1218790-57-8)
- (2'-Fluoro-[1,1'-biphenyl]-4-yl)boronic acid (CAS 1383531-49-4)
- 2-Fluoro-biphenyl-5-ylboronic acid (CAS 1383532-12-4)
- (4'-Fluoro-[1,1'-biphenyl]-3-yl)boronic acid (CAS 159020-61-8)
- 2-Fluoro-4-biphenylylboronic acid (CAS 178305-99-2)
- (4'-Fluoro-[1,1'-biphenyl]-2-yl)boronic acid (CAS 179526-94-4)
- 3-Fluoro-4-biphenylboronic acid (CAS 409108-13-0)
Recommended Standards
- 4,6-Dichloroisatin (CAS 18711-15-4)
- (4-Methoxy-5-(methoxycarbonyl)thiophen-2-yl)boronic acid (CAS 2251714-63-1)
- 4,7-Dichloroisatin (CAS 18711-13-2)
- (4-methylsulfonyloxyphenyl)boronic acid (CAS 957035-04-0)
- Anthracene-9-sulfonyl chloride (CAS 53973-96-9)
- [(2S)-4-Benzylpiperazin-2-yl]methanol (CAS 149715-45-7)
- 5-Chloro-2-(methylimino)-1,2-dihydropyridine-3-carbonitrile (CAS 1427460-56-7)
- 2-Methoxy-5-(pyridin-4-yl)aniline (CAS 104994-92-5)
- Benedictine (CAS 487-91-2)
- 1-(2-bromophenyl)-2,5-dimethyl-1H-pyrrole-3-carboxylic acid (CAS 923863-66-5)
- Methyl 2-isopropyl-1-oxaspiro[2.4]heptane-2-carboxylate (CAS 1508946-27-7)
- 1-(2,4-Difluorophenyl)-5-methyl-1h-pyrazole-4-carboxylic acid (CAS 187999-20-8)
- 3-Bromo-2-(difluoromethyl)pyridine (CAS 1211520-77-2)
- Semaglutide Impurity 189 (CAS CATO-C4X-2226189)
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