Glipizide Impurity 18 CAS 122-05-4
| CAS No. | 122-05-4 |
| Molecular Formula | C6H4N2O4 |
| Molecular Weight | 168.11 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 168.11 g/mol gives Glipizide Impurity 18 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Glipizide Impurity 18 (CAS 122-05-4) is a certified pharmaceutical impurity reference standard with the molecular formula C6H4N2O4 and a molecular weight of 168.11 g/mol.
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, Glipizide Impurity 18 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 168.11 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H4N2O4 |
| Molecular Weight | 168.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >80% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 2 |
Related Glipizide Standards
Recommended Standards
- Nicotinic Acid EP Impurity F (CAS 2047-49-6)
- 4-Nitropicolinicacid (CAS 13509-19-8)
- Bortezomib Impurity 42 (CAS 89-01-0)
- Uric Acid (CAS 69-93-2)
- Estradiol Impurity 44 (CAS CATO-C4X-163644)
- Butylphthalide Impurity 33 (CAS CATO-C4X-181333)
- Macitentan Impurity 23 (CAS CATO-C4X-117523)
- Tridecan-7-amine (CAS 22513-16-2)
- Phenylbutazone EP Impurity A (CAS 3583-64-0)
- Tetrahydro-2H-thiopyran-2-carboxamide (CAS 18729-18-5)
- 3,4-Dichloro-4-pyrrolidinomethyl benzophenone (CAS 898776-85-7)
- 3-Chloro-7-(dibutylamino)quinoline-8-carbonitrile (CAS 88346-98-9)
- 168551-88-0 2-(2-Aminothiazole-4-yl)-2-[2-(tert-butoxycarbonyl)-methoxyimino]acetic acid C11H17N3O5S (CAS 168551-88-0)
- D-Gln24-Tirzepatide (CAS CATO-CPTD788910)
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