Estradiol Impurity 44 CAS CATO-C4X-163644
| CAS No. | CATO-C4X-163644 |
| Molecular Formula | C19H24O2 |
| Molecular Weight | 284.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Estradiol Impurity 44 is closely related to a steroid core, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Estradiol Impurity 44 (CAS CATO-C4X-163644), a pharmacopoeial impurity reference standard (molecular formula C19H24O2, MW 284.39 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Estradiol Impurity 44 (C19H24O2) contains a steroid core, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 284.39 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Estradiol Impurity 44 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H24O2 |
| Molecular Weight | 284.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Estradiol Standards
- Estradiol Impurity N1 (CAS 4011-48-7)
- Estradiol Impurity 26 (CAS CATO-C4X-163626)
- Estradiol Impurity 27 (CAS CATO-C4X-163627)
- Estradiol Impurity 30 (CAS 4954-08-9)
- Estradiol Impurity 51 (CAS 165609-57-4)
- Estradiol Impurity 5 (CAS 1476-34-2)
- Estradiol USP Related Compound C (CAS 571-92-6)
- Estradiol Impurity 4 (CAS 566-75-6)
Recommended Standards
- Exemestane Impurity 2 (CAS 1035-69-4)
- Testosterone EP Impurity G (CAS 897-06-3)
- Progesterone Impurity 74 (CAS 96893-14-0)
- Levonorgestrel Impurity 34 (CAS CATO-C4X-167734)
- Pyronaridine Impurity 6 (CAS CATO-C4X-29786)
- Goserelin Impurity N36 (CAS 1426173-74-1)
- Desloratadine Impurity 64 (CAS CATO-C4X-143064)
- lithium(1+) ion 2-{[(tert-butoxy)carbonyl](methyl)amino}-4-hydroxy-4-methylpentanoate (CAS 1803561-87-6)
- 3-Chloro-2-(3,5-dimethylpyrazol-1-yl)pyridine (CAS 1150164-90-1)
- (2S,3R,4R,5R)-5-(benzyloxymethyl)-4-[tert-butyl(dimethyl)silyl]oxy-2-(3-fluorophenyl)-3-methoxy-tetrahydrofuran-2-ol (CAS 1583260-03-0)
- 2-({[(9h-fluoren-9-yl)methoxy]carbonyl}(prop-2-yn-1-yl)amino)acetic acid (CAS 1033622-38-6)
- 4,5,6,7-Tetrabromo-3,3-bis(4-hydroxyphenyl)isobenzofuran-1(3H)-one (CAS 13027-28-6)
- (S)-2,2'-Diiodo-1,1'-binaphthalene (CAS 86688-07-5)
- Semaglutide impurity 256 (CAS CATO-C4X-2226256)
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