Bortezomib Impurity 42 CAS 89-01-0
| CAS No. | 89-01-0 |
| Molecular Formula | C6H4N2O4 |
| Molecular Weight | 168.11 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Bortezomib Impurity 42 (C6H4N2O4) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Bortezomib Impurity 42 (CAS 89-01-0, C6H4N2O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Bortezomib Impurity 42 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H4N2O4 |
| Molecular Weight | 168.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 2 |
Related Bortezomib Standards
- Bortezomib Impurity 21 (CAS 18680-27-8)
- Bortezomib Impurity 77 (CAS 103435-88-7)
- Bortezomib Impurity 44 (CAS 78-77-3)
- Bortezomib Impurity 15 (CAS 1259365-04-2)
- Bortezomib Impurity 41 (CAS 4664-57-7)
- Bortezomib Impurity N17 (CAS 84110-40-7)
- Bortezomib Impurity N32 (CAS 84110-34-9)
- Bortezomib Impurity 11 (CAS CATO-C4X-107211)
Recommended Standards
- (E)-4,4,4-trifluorobut-2-enoic acid 4,4,4-trifluoro Crotonic acid 406-10-0 (CAS 406-10-0)
- Nicotinic Acid EP Impurity F (CAS 2047-49-6)
- 1,1,1-trifluorohexane-2,4-dione 1-(Trifluoroacetyl)butan-2-one 2,4-Dioxo-1,1,1-trifluorohexane 400-54-4 (CAS 400-54-4)
- Glipizide Impurity 18 (CAS 122-05-4)
- Nefopam Impurity 33 (CAS CATO-C4X-283733)
- Peramivir Impurity 8 (CAS 383910-24-5)
- Arbidol Impurity 60 (CAS 151455-32-2(free base))
- Antibiotic PF 1052 (CAS 147317-15-5)
- 3-Formyl-4-hydroxypicolinic acid (CAS 1289035-71-7)
- 2-Chloro-N-cyclopropyl-N-((1-methylpiperidin-3-yl)methyl)acetamide (CAS 1353970-53-2)
- 2-Bromoterephthalaldehyde (CAS 90001-43-7)
- Roxadustat Impurity 30 (CAS CATO-C4X-221330)
- GHRP-2 Acetate (CAS 158861-67-7(Free Base))
- Semaglutide impurity 201 (CAS CATO-C4X-2226201)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com