Pioglitazone impurity 30 CAS 1229114-66-2
| CAS No. | 1229114-66-2 |
| Molecular Formula | C18H21NO3S |
| Molecular Weight | 331.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Pioglitazone impurity 30 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Pioglitazone impurity 30 (CAS 1229114-66-2), a pharmacopoeial impurity reference standard (molecular formula C18H21NO3S, MW 331.43 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C18H21NO3S, Pioglitazone impurity 30 contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 331.43 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C18H21NO3S |
| Molecular Weight | 331.43 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Pioglitazone Standards
- Pioglitazone impurity 45 (CAS CATO-C4X-138345)
- Pioglitazone impurity 48 (CAS CATO-C4X-138348)
- Pioglitazone EP Impurity E (CAS 868754-42-1)
- Pioglitazone impurity 43 (CAS CATO-C4X-138343)
- Pioglitazone Impurity 22 (CAS CATO-C4X-138322)
- Pioglitazone impurity 42 (CAS CATO-C4X-138342)
- Pioglitazone impurity 34 (CAS CATO-C4X-138334)
- (5Z)-Pioglitazone EP Impurity B (CAS 136401-69-9)
Recommended Standards
- N-Cyclopropyl-2-(5-(hydroxymethyl)-2-(phenethylthio)-1H-imidazol-1-yl)acetamide (CAS 921568-34-5)
- Peramivir-d3 (CAS 1246816-86-3)
- N-Cyclopropyl-2-(5-(hydroxymethyl)-2-((2-methylbenzyl)thio)-1H-imidazol-1-yl)acetamide (CAS 921568-10-7)
- 7-Hydroxy Granisetron-d3 (CAS 133841-15-3(non-labelled))
- Bepotastine Impurity 8 (CAS CATO-C4X-18398)
- Ketoconazole Impurity N15 (CAS 170210-42-1)
- Budesonide EP Impurity E (CAS 131918-64-4)
- 2-(1-Ethyl-1h-pyrazol-5-yl)ethan-1-amine (CAS 1262865-38-2)
- 4-CHloro-6-(pyrrolidin-3-yloxy)pyrimidin-2-amine dihydrochloride (CAS 2109195-06-2)
- 5-(Tetrahydro-2h-pyran-4-yl)-1,2,4-oxadiazole-3-carboxylic acid (CAS 1339612-02-0)
- 4-(3-Methoxypropoxy)-2-methylaniline (CAS 946785-95-1)
- tert-Butyl (E)-(4-phenylbut-3-en-2-yl)carbamate (CAS 129389-43-1)
- D-tert-Leucinol (CAS 112245-09-7)
- Semaglutide impurity 83 (CAS CATO-C4X-222683)
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