Rotigotine EP Impurity H HCl CAS 1232344-37-4
| CAS No. | 1232344-37-4 |
| Molecular Formula | C20H27NOS |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Rotigotine EP Impurity H HCl (CAS 1232344-37-4, C20H27NOSHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution, Rotigotine EP Impurity H HCl is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 365.96 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures Rotigotine EP Impurity H HCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H27NOS HCl |
| Molecular Weight | 365.96 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Rotigotine Standards
- Rotigotine Impurity 11 (CAS 101403-24-1)
- Rotigotine impurity 23 (CAS 101470-23-9)
- Rotigotine EP Impurity B Hydrochloride (CAS 101470-23-9（free base）)
- Rotigotine Racemate HCl (CAS 102120-99-0)
- Rotigotine Impurity 40 (CAS 102121-00-6)
- Rotigotine EP Impurity A (CAS 112835-48-0)
- Rotigotine EP Impurity A HCl (CAS 112835-48-0（free base）)
- Rotigotine EP Impurity H (CAS 1148154-91-9)
Recommended Standards
- Aripiprazole Impurity 49 (CAS 882880-12-8)
- Agomelatine Impurity 22 (CAS 1353100-18-1)
- Moxifloxacin impurity 191 (CAS CATO-C4X-1074191)
- N-Ethyl-3-fluoro-5-hydroxybenzamide (CAS 1881320-67-7)
- 1-(2-Methylphenyl)-2-propyn-1-ol (CAS 139416-71-0)
- 6-Oxo-6,7-dihydro-5H-pyridazino[3,4-b][1,4]oxazine-3-carbaldehyde (CAS 1003947-30-5)
- N-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-((3-(4-methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetamide (CAS 477330-72-6)
- 2,6-Difluoro-3-hydroxybenzonitrile (CAS 946796-26-5)
- 2,5-Dichloro-3-(difluoromethoxy)benzyl bromide (CAS 1804883-85-9)
- Peptide 438 (CAS CATO-CPTD788438)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com