1-[Chloro(difluoro)methoxy]-2,4-difluoro-benzene CAS 123572-68-9
| CAS No. | 123572-68-9 |
| Molecular Formula | C7H3ClF4O |
| Molecular Weight | 214.54 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 1-[Chloro(difluoro)methoxy]-2,4-difluoro-benzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
1-[Chloro(difluoro)methoxy]-2,4-difluoro-benzene (CAS 123572-68-9), molecular formula C7H3ClF4O and molecular weight 214.54 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 1-[Chloro(difluoro)methoxy]-2,4-difluoro-benzene (C7H3ClF4O) contains a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 214.54 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C7H3ClF4O |
| Molecular Weight | 214.54 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 1-Chloro-4-fluoro-2-(trifluoromethoxy)benzene (CAS 114021-45-3)
- 2-Chloro-6-fluoro-4-(trifluoromethyl)phenol (CAS 116640-09-6)
- 2-Chloro-6-fluoro-3-(trifluoromethyl)phenol (CAS 1254781-50-4)
- 1-Chloro-3-(difluoromethoxy)-2,4-difluorobenzene (CAS 1261769-13-4)
- 1-Chloro-5-(difluoromethoxy)-2,4-difluorobenzene (CAS 1261808-36-9)
- 2-Chloro-5-(difluoromethoxy)-1,3-difluorobenzene (CAS 1261846-38-1)
- 2-Chloro-3-(difluoromethoxy)-1,4-difluoro-benzene (CAS 1261869-12-8)
- 1-Chloro-4-(difluoromethoxy)-2,5-difluorobenzene (CAS 1261884-44-9)
Recommended Standards
- 5-Chloro-6-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione (CAS 85730-40-1)
- 3-Chloro-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid (CAS 1322794-24-0)
- 52764-12-2 6-Bromo-2-chloropyridin-3-ol C5H3BrClNO V6405 (CAS 52764-12-2)
- 3,3,3-Trifluoro-2-(trifluoromethyl)propionyl chloride (CAS 382-19-4)
- 3-Methyl-5-(methylthio)-3,6-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one (CAS 65023-35-0)
- 2-(Methoxymethyl)cyclohexanone (CAS 58173-92-5)
- 4-Chloro-6-(2,4-dichlorophenoxy)-3-phenylpyridazine (CAS 477872-34-7)
- 3-(5-Methyl-1h-1,2,4-triazol-3-yl)propan-1-amine hydrochloride (CAS 1354953-35-7)
- Capmatinib Impurity 4 (CAS 1243392-80-4)
- 3-((4-Chlorophenyl)thio)propanenitrile (CAS 5307-86-8)
- 1,3,7,9-Tetramethyl-N5,N5,N11,N11-tetrakis(1-phenylethyl)-4,6,10,12-tetraoxa-5,11-diphosphadibenzo[ef,kl]heptalene-5,11-diamine (CAS 1449007-63-9)
- Betamethasone Impurity 89 (CAS CATO-C4X-143789)
- 2-Isoxazol-3-yl-phenol (CAS 61348-48-9)
- Tau Peptide (274-288) trifluoroacetate salt (CAS 330456-39-8)
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