Metformin EP impurity F Tetrahydrofuran Solution CAS 124-40-3 (free base)

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.124-40-3 (free base)
Molecular FormulaC4H8O
Molecular WeightN/A
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Metformin EP impurity F Tetrahydrofuran Solution CAS 124-40-3 (free base) chemical structure

Description

As a process- or degradation-related impurity, Metformin EP impurity F Tetrahydrofuran Solution (CAS 124-40-3 (free base), C4H8OC2H7N) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.

Owing to an amide group, a hydroxyl group, an ether linkage, Metformin EP impurity F Tetrahydrofuran Solution is typically white to off-white liquid. Its solid-state physicochemical attributes — including a molecular weight of 117.19 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC4H8O C2H7N
Molecular Weight117.19 g/mol
Purity>95%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)0.0
Nitrogen Atoms1

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