Roflumilast impurity 25 CAS 1243391-44-7
| CAS No. | 1243391-44-7 |
| Molecular Formula | C11H12O4 |
| Molecular Weight | 208.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Roflumilast impurity 25 (CAS 1243391-44-7) is a certified pharmaceutical impurity reference standard with the molecular formula C11H12O4 and a molecular weight of 208.21 g/mol.
Based on its molecular formula C11H12O4, Roflumilast impurity 25 contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 208.21 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Roflumilast impurity 25 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H12O4 |
| Molecular Weight | 208.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
Related Roflumilast Standards
- Roflumilast Impurity 11 (CAS 159783-78-5)
- Roflumilast Impurity 13 (CAS 53173-70-9)
- Roflumilast impurity 19 (CAS 151103-08-1)
- Roflumilast Impurity 17 (CAS 91872-02-5)
- Roflumilast Impurity 10 (CAS 127842-54-0)
- Roflumilast impurity 17 (CAS 151103-09-2)
- Roflumilast impurity 21 (CAS 162401-78-7)
- Roflumilast Impurity 41 (CAS 1882067-43-7)
Recommended Standards
- Linezolid Impurity 69 (CAS 10389-51-2)
- Ivabradine impurity 86 (CAS 1220993-44-1)
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- Deferasirox Impurity 10 (CAS 1395346-28-7)
- Tapentadol Impurity 13 (CAS CATO-C4X-209913)
- Esomeprazole Impurity 52 (CAS 704910-88-3)
- (3S,4S)-4-Methyltetrahydrofuran-3-ol (CAS 1932610-18-8)
- 2-Chlorobenzyl alcohol (CAS 17849-38-6)
- (R)-N-Butyl-2-(3-hydroxypyrrolidin-1-yl)acetamide (CAS 1355623-32-3)
- Pyrido[2,3-d]pyrimidine-4-carboxylic acid (CAS 2168847-74-1)
- 4-Bromo-3-fluoro-N,N-dimethylbenzenesulfonamide (CAS 779331-34-9)
- 4-Fluoro-2-nitrobenzenethiol (CAS 654063-68-0)
- Tirzepatide Impurity 10 (CAS CATO-C4X-324010)
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