Atorvastatin Impurity 82 CAS 125971-96-2
| CAS No. | 125971-96-2 |
| Molecular Formula | C26H24FNO3 |
| Molecular Weight | 417.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Atorvastatin Impurity 82 (CAS 125971-96-2), a pharmacopoeial impurity reference standard (molecular formula C26H24FNO3, MW 417.47 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Atorvastatin Impurity 82 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 417.47 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), Atorvastatin Impurity 82 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H24FNO3 |
| Molecular Weight | 417.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Atorvastatin Standards
- Atorvastatin Impurity 103 (CAS 1797905-42-0)
- Atorvastatin Oxirane Impurity (CAS 1246818-88-1)
- Atorvastatin Impurity 154 (CAS 1331869-19-2)
- Atorvastatin Impurity 104 (CAS CATO-C4X-1132104)
- Atorvastatin EP Impurity D (CAS 148146-51-4)
- Atorvastatin Impurity 145 (CAS CATO-C4X-1132145)
- Atorvastatin Impurity 27 (CAS 693793-82-7)
- Atorvastatin Impurity 26 (CAS 444577-70-2)
Recommended Standards
- (R)-2-(((Benzyloxy)carbonyl)amino)-1-((S)-2,5-dihydrofuran-2-yl)ethyl 4-methylbenzenesulfonate (CAS 1001547-78-9)
- 2-hydroxy-S-(4-{6-[(oxan-4-yl)amino]imidazo[1,2-b]pyridazin-3-yl}phenyl)ethane-1-sulfonamido (CAS 1012345-91-3)
- Citalopram Impurity 96 (CAS CATO-C4X-110996)
- 4-Fluoro-N-(6-((4-oxo-4-(thiazol-2-ylamino)butyl)thio)pyridazin-3-yl)benzamide (CAS 1105218-91-4)
- Betamethasone Impurity 136 (CAS CATO-C4X-1437136)
- Clindamycin Phosphate EP Impurity I (CAS 1309048-48-3)
- Clopidogrel Impurity 9 (CAS 532987-11-4)
- 2-(Isoquinolin-5-yloxy)ethanol (CAS 313656-28-9)
- 1,1,1-Trifluoro-6-(2-hydroxyphenyl)hex-5-ene-2,4-dione (CAS 885371-79-9)
- (S)-6,7-Dihydro-5H-cyclopenta[c]pyridin-5-ol (CAS 2096419-37-1)
- 1-(2-Bromophenyl)carbonyl-4-methylpiperazine (CAS 331845-66-0)
- 2-(Difluoromethyl)-3-fluoro-4-hydroxypyridine-5-acetic acid (CAS 1805191-04-1)
- 5-Cyano-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid (CAS 800401-88-1)
- a-Bag Cell Peptide (1-8) (CAS 87549-53-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com