Cobicistat impurity 11 CAS 1247119-33-0
| CAS No. | 1247119-33-0 |
| Molecular Formula | C23H27N3O2S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Cobicistat impurity 11 (CAS 1247119-33-0, C23H27N3O2SHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C23H27N3O2SHCl, Cobicistat impurity 11 contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 446.01 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Cobicistat impurity 11 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H27N3O2S HCl |
| Molecular Weight | 446.01 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Cobicistat Standards
- Cobicistat (CAS 1004316-88-4)
- Cobicistat impurity (CAS 1004316-92-0)
- Cobicistat impurity 7 (CAS 1004316-93-1)
- Cobicistat impurity 14 (CAS 1051463-15-0)
- Cobicistat impurity 12 (CAS 1051463-40-1)
- Cobicistat Impurity 3 (CAS 1051463-82-1)
- Cobicistat Impurity N1 (CAS 1247119-35-2)
- Cobicistat impurity 6 (CAS 1370406-84-0)
Recommended Standards
- Oseltamivir Impurity 93 (CAS CATO-C4X-172093)
- Loratadine Impurity 95 (CAS CATO-C4X-142695)
- Indacaterol Impurity 50 HCl (CAS 1384189-12-1(Free Base))
- (3-(3-Nitrophenylamino)prop-2-enylidene)3-nitrophenylamine, hydrochloride (CAS 1274948-08-1)
- (9E,11E,13R)-13-Hydroxyoctadeca-9,11-dienoic acid (CAS 10219-69-9)
- Z-cha-oh.dcha (CAS 54594-40-0)
- (3R)-3-Methyl-6-phenyl-1,2-thiazinane 1,1-dioxide (CAS 1537863-75-4)
- 2-(4-(Trifluoromethyl)phenoxy)ethanamine (CAS 681482-61-1)
- 2-Methyl-2-butene-2-<SUP>13</SUP>C (CAS 1173023-18-1)
- [D-His]-Semaglutide B (x TFA Salt) (CAS CATO-C4X-2226117)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com