Letrozole Impurity 39 CAS 28188-41-2
| CAS No. | 28188-41-2 |
| Molecular Formula | C8H6BrN |
| Molecular Weight | 196.04 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Letrozole Impurity 39 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Letrozole Impurity 39 (CAS 28188-41-2), a pharmacopoeial impurity reference standard (molecular formula C8H6BrN, MW 196.04 g/mol) used for the identification and quantification of trace impurities in APIs.
Letrozole Impurity 39 (C8H6BrN) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C8H6BrN |
| Molecular Weight | 196.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Letrozole Standards
- Letrozole Impurity 28 (CAS 46209-39-6)
- Letrozole Impurity 24 (CAS CATO-C4X-182924)
- Letrozole Impurity 33 (CAS 1461654-89-6)
- Letrozole Impurity 25 (CAS 1250126-45-4)
- Letrozole Impurity 15 (CAS 74231-65-5)
- Letrozole Impurity 17 (CAS 112809-27-5)
- Letrozole Impurity 22 (CAS 876728-37-9)
- Letrozole Impurity 23 (CAS 876316-41-5)
Recommended Standards
- Alogliptin Impurity 37 (CAS 22115-41-9)
- 2,3-Dihydro-5-furanoboronic acid pinacol ester (CAS 1046812-02-5)
- 4-Cyanobenzyl Bromide (CAS 17201-43-3)
- 2-(4,5-Dihydrofuran-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1046812-03-6)
- Daprodustat Impurity 13 (CAS 4833-41-4)
- Melitracen Impurity 6 (CAS 18792-73-9)
- Methylene blue Impurity 5 (CAS CATO-C4X-18965)
- tert-Butyl 3-(hydroxymethyl)-[1,4'-bipiperidine]-1'-carboxylate (CAS 864293-17-4)
- 2'-Chloro-[1,1'-biphenyl]-2-carboxylicacid (CAS 14498-95-4)
- Strontium hydroxide octahydrate (CAS 1311-10-0)
- Fesoterodine Impurity 25 (CAS 89840-84-6)
- 2-(4-Chloro-2-(isoxazol-5-yl)phenoxy)acetic Acid (CAS 882689-21-6)
- 3-hydroxy-4-[(4-methylphenyl)diazenyl]-2-naphthoic acid 82896-77-3 (CAS 82896-77-3)
- Tirzepatide Impurity 10 (CAS CATO-C4X-324010)
Why CATO?
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