Ezetimibe Impurity 124 CAS 1251741-03-3
| CAS No. | 1251741-03-3 |
| Molecular Formula | C24H23NO3 |
| Molecular Weight | 373.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Ezetimibe Impurity 124 (CAS 1251741-03-3), a pharmacopoeial impurity reference standard (molecular formula C24H23NO3, MW 373.44 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Ezetimibe Impurity 124 (C24H23NO3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Ezetimibe Impurity 124 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H23NO3 |
| Molecular Weight | 373.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 1 |
Related Ezetimibe Standards
- Ezetimibe Impurity 63 (CAS CATO-C4X-109863)
- Ezetimibe Impurity 125 (CAS 439080-96-3)
- Ezetimibe Impurity 139 (CAS CATO-C4X-1098139)
- Ezetimibe Impurity 24 (CAS 528565-93-7)
- Ezetimibe Impurity 25 (CAS 404874-94-8)
- Ezetimibe Impurity 26 (CAS 1612153-32-8)
- Ezetimibe Impurity 42 (CAS 189028-95-3)
- Ezetimibe Impurity 93 (CAS CATO-C4X-109893)
Recommended Standards
- Prasugrel EP Impurity C (CAS 1391194-50-5)
- Mivacurium chloride Impurity 24 (CAS 188956-91-4)
- Prasugrel EP Impurity B (CAS 1391194-39-0)
- Mivacurium chloride Impurity 26 (CAS 73554-57-1)
- Lamivudine Impurity B (CAS 141434-39-1)
- Olmesartan Impurity 62 (CAS 91526-17-9)
- Relugolix Impurity 9 (CAS CATO-C4X-24299)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com