4,4-Difluoropiperidin-2-one CAS 1255666-74-0

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4,4-Difluoropiperidin-2-one.

4,4-Difluoropiperidin-2-one (CAS 1255666-74-0), molecular formula C5H7F2NO and molecular weight 135.11 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 4,4-Difluoropiperidin-2-one is typically white to off-white liquid. Its solid-state physicochemical attributes — including a molecular weight of 135.11 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4,4-Difluoropiperidin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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