2-Chloro-5-(3-(trifluoromethoxy)phenyl)isonicotinic acid CAS 1258621-11-2
| CAS No. | 1258621-11-2 |
| Molecular Formula | C13H7ClF3NO3 |
| Molecular Weight | 317.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 317.65 g/mol gives 2-Chloro-5-(3-(trifluoromethoxy)phenyl)isonicotinic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-Chloro-5-(3-(trifluoromethoxy)phenyl)isonicotinic acid (CAS 1258621-11-2), molecular formula C13H7ClF3NO3 and molecular weight 317.65 g/mol, is a CATO reference standard with documented purity and traceability.
2-Chloro-5-(3-(trifluoromethoxy)phenyl)isonicotinic acid (C13H7ClF3NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Chloro-5-(3-(trifluoromethoxy)phenyl)isonicotinic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H7ClF3NO3 |
| Molecular Weight | 317.65 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)benzoic acid (CAS 105626-87-7)
- 4-Chloro-6-(4-trifluoromethoxyphenylamino)pyrimidine-5-carbaldehyde (CAS 1160701-79-0)
- 2-Chloro-5-(3-(trifluoromethoxy)phenyl)nicotinic acid (CAS 1258616-79-3)
- 5-Chloro-6-(3-(trifluoromethoxy)phenyl)nicotinic acid (CAS 1261485-75-9)
- 2-Chloro-5-(4-(trifluoromethoxy)phenyl)isonicotinic acid (CAS 1261586-34-8)
- 2-Chloro-5-(4-(trifluoromethoxy)phenyl)nicotinic acid (CAS 1261763-21-6)
- 5-Chloro-2-[3-(trifluoromethyl)-phenoxy]nicotinic acid (CAS 1338494-58-8)
- 2-Chloro-5-((4-(trifluoromethyl)pyrimidin-2-yl)amino)benzoic acid (CAS 1456213-79-8)
Recommended Standards
- 2-(5-Bromothiophen-2-yl)-4-chloro-5-ethyl-6-methylpyrimidine (CAS 915084-50-3)
- 2,4,6-Trichlorophenyl 1-butanesulfonate (CAS 1171919-49-5)
- 5-Bromo-2-chloro-N-cyclohexylisonicotinamide (CAS 2005691-09-6)
- 1-(4-Bromo-2-chlorobenzyl)-4-ethylpiperazine (CAS 1704074-23-6)
- 951894-42-1 2-Bromo-3-(2-chloro-4-fluorophenyl)-1-propene MFCD09801308 (CAS 951894-42-1)
- 6-(2-(4-Fluorophenyl)-2-oxoethyl)nicotinonitrile (CAS 145835-09-2)
- 6-(3,5-Difluorophenyl)-nicotinic acid (CAS 1033844-89-1)
- N-Benzyl-2-chloro-5-(chloromethyl)-3-methoxy-N-methylaniline (CAS 67402-49-7)
- 4-(3-Fluoro-4-methylbenzoyl)-3-hydroxy-5-(4-propoxyphenyl)-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one (CAS 618073-92-0)
- (S)-1-(2-bromo-4-(trifluoromethyl)phenyl)ethan-1-ol (CAS 2227642-96-6)
- N1-(3-(trifluoromethyl)phenyl)propane-1,3-diamine (CAS 124438-61-5)
- (S,R,S)-AHPC-Boc (CAS 1448189-98-7)
- 199926-21-1 KS-000018SK L-Lysine, hydrate (CAS 199926-21-1)
- Semaglutide Impurity 166 (CAS 1395881-03-4)
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