Fosfomycin Trometamol EP Impurity D TFA salt CAS 1262243-12-8(Free Base)
| CAS No. | 1262243-12-8(Free Base) |
| Molecular Formula | C10H25NO11P2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Fosfomycin Trometamol EP Impurity D TFA salt is closely related to a carbohydrate-derived structure, an amide group, a phosphate ester group, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Fosfomycin Trometamol EP Impurity D TFA salt (CAS 1262243-12-8(Free Base), C10H25NO11P2C2HF3O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Fosfomycin Trometamol EP Impurity D TFA salt (C10H25NO11P2C2HF3O2) is characterized by a carbohydrate-derived structure, an amide group, a phosphate ester group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Fosfomycin Trometamol EP Impurity D TFA salt under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H25NO11P2 C2HF3O2 |
| Molecular Weight | 511.28 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | -1.0 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fosfomycin Standards
- Fosfomycin EP Impurity C (Barium Salt) (CAS 114252-50-5)
- Fosfomycin Open Ring Impurity A (CAS 1160525-87-0)
- Rac Fosfomycin-13C3 Benzylamine Salt (CAS 1216461-18-5)
- Fosfomycin Trometamol EP Impurity B (CAS 1262243-11-7)
- Fosfomycin Trometamol EP Impurity B TEA Salt (CAS 1262243-11-7(free base))
- Fosfomycin Trometamol EP Impurity D (CAS 1262243-12-8)
- Fosfomycin Trometamol EP Impurity D TEA salt(Discontinued,See C4X-13165) (CAS 1262243-12-8(Free Acid))
- Fosfomycin Impurity 66 (CAS 13086-84-5)
Recommended Standards
- Nicorandil Impurity 12 (CAS 83440-03-3)
- Netupitant Impurity 60 (CAS CATO-C4X-122360)
- Terbutaline impurity 114 (CAS CATO-C4X-1183114)
- N-(4-chlorophenyl)-2-(3-(thiophen-2-yl)-4,5-dihydroisoxazole-5-carbonyl)hydrazine-1-carboxamide (CAS 478259-23-3)
- 3-Amino-1-methyl-4,5-dihydropyrido[1,2-a][1,3]diazepine-2,7(1H,3H)-dione (CAS 2222856-71-3)
- N1,N1-diethyl-N2-[2-(2-methoxyphenoxy)ethyl]-1,2-ethanediamine (CAS 1226362-84-0)
- Triamterene-d5 (CAS 1189922-23-3)
- 4-[(4-Chlorophenoxy)methyl]piperidine (CAS 63608-33-3)
- Fluorinert FC-40 (CAS 51142-49-5)
- Liraglutide(8-31)TFA Salt (CAS CATO-C4X-19922)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com