Beclomethasone dipropionate Impurity 29 CAS CATO-C4X-147429

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-147429
Molecular FormulaC22H28O5
Molecular Weight372.45 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Beclomethasone dipropionate Impurity 29 CAS CATO-C4X-147429 chemical structure

Description

The occurrence of Beclomethasone dipropionate Impurity 29 is closely related to a flavonoid core, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

Beclomethasone dipropionate Impurity 29 (CAS CATO-C4X-147429) is a certified pharmaceutical impurity reference standard with the molecular formula C22H28O5 and a molecular weight of 372.45 g/mol.

Structurally, Beclomethasone dipropionate Impurity 29 (C22H28O5) contains a flavonoid core, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 372.45 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

As a certified reference material (CRM), Beclomethasone dipropionate Impurity 29 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC22H28O5
Molecular Weight372.45 g/mol
AppearancePale yellow to yellow crystalline powder
Purity>95%
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present

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