Fosaprepitant Impurity 21 CAS 265121-01-5
| CAS No. | 265121-01-5 |
| Molecular Formula | C37H34F7N4O6P |
| Molecular Weight | 794.65 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Fosaprepitant Impurity 21.
Fosaprepitant Impurity 21 (CAS 265121-01-5) is a certified pharmaceutical impurity reference standard with the molecular formula C37H34F7N4O6P and a molecular weight of 794.65 g/mol.
Structurally, Fosaprepitant Impurity 21 (C37H34F7N4O6P) contains a nitrogen-containing heterocyclic scaffold, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 19.5, corresponding to approximately 19 ring(s) or double-bond equivalent(s). With a molecular weight of 794.65 g/mol, it falls into the high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Fosaprepitant Impurity 21 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C37H34F7N4O6P |
| Molecular Weight | 794.65 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 19.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Fosaprepitant Standards
- Fosaprepitant Impurity 20 (CAS CATO-C4X-116820)
- Fosaprepitant impurity 58 (CAS CATO-C4X-116858)
- Fosaprepitant Impurity 51 (CAS CATO-C4X-116851)
- Fosaprepitant Impurity 12 (CAS 2035475-10-4)
- Fosaprepitant Impurity 22 (CAS CATO-C4X-116822)
- Fosaprepitant Impurity 42 (CAS CATO-C4X-116842)
- Fosaprepitant Impurity 44 (CAS CATO-C4X-116844)
- Fosaprepitant Impurity 45 (CAS CATO-C4X-116845)
Recommended Standards
- Dichloro [(R)-(+)-2,2-bis(diphenylphosphino)-1,1-binaphathyl] ruthenium(II) (CAS 132071-87-5)
- 2,3-Dibromo-1,4-dichlorobutane (CAS 4911-46-0)
- (11aS)-3,7-Bis[3,5-bis(trifluoromethyl)phenyl]-10,11,12,13-tetrahydro-10,10,13,13-tetramethyl-5-hydroxy-5-oxide-diindeno[7,1-de:1',7'-fg][1,3,2]dioxaphosphocin (CAS 2250167-83-8)
- 5,10,15,20-Tetrakis(4-nitrophenyl)porphyrin (CAS 22843-73-8)
- Ivacaftor impurity 17 (CAS CATO-C4X-296417)
- Mitiglinide Impurity 7 (CAS 21307-97-1)
- Avatrombopag impurity 129 (CAS CATO-C4X-2234129)
- 145918-59-8 7,8,9,9-Tetradehydroisolariciresinol (CAS 145918-59-8)
- 3-(5-Chloro-8-methoxy-4-oxoquinolin-1(4H)-yl)propanehydrazide (CAS 1315373-66-0)
- Pomalidomide Impurity 8 (CAS 603-11-2)
- 5-Bromo-2-(tetrahydro-2-furanylmethoxy)aniline (CAS 946664-90-0)
- 5-Oxo-5H-thiazolo[3,2-a]pyridine-2-carboxylic acid (CAS 2387596-21-4)
- 5-Oxopiperidine-2-carboxylic acid (CAS 789448-80-2)
- D-Ser12-Semaglutide (CAS CATO-C4X-2226240)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com