Thiamphenicol Impurity 9 CAS 126429-09-2
| CAS No. | 126429-09-2 |
| Molecular Formula | C12H13Cl2NO4S |
| Molecular Weight | 338.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Thiamphenicol Impurity 9 (CAS 126429-09-2, C12H13Cl2NO4S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Thiamphenicol Impurity 9 (C12H13Cl2NO4S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 338.21 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Thiamphenicol Impurity 9 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H13Cl2NO4S |
| Molecular Weight | 338.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Thiamphenicol Standards
- Thiamphenicol Impurity 10 (CAS 126813-11-4)
- Thiamphenicol (CAS 847-25-6)
- Thiamphenicol Impurity 2 (CAS 19934-71-5)
- Thiamphenicol Impurity 4 (CAS 27348-52-3)
- Thiamphenicol Impurity 6 (CAS 21079-44-7)
- Thiamphenicol (CAS 15318-45-3)
- Thiamphenicol-Methyl-D3 (CAS CATO-CCAD300798)
- ent-Thiamphenicol-d3 (CAS 1217723-41-5)
Recommended Standards
- AICAR Monophosphate (CAS 3031-94-5)
- N-Pyridin-4-ylmethyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzamide (CAS 864754-25-6)
- 5-Bromo-2-ethoxy-n-(3-hydroxypropyl)benzenesulfonamide (CAS 1018158-47-8)
- N-Pyridin-2-ylmethyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzamide (CAS 864754-23-4)
- Dotinurad Impurity 200 (CAS CATO-C4X-2494200)
- N-Nitroso Venlafaxine EP Impurity H (Mixture of Diastereomers) (CAS CATO-C4X-143453)
- Voriconazole Impurity 53 (CAS 759-67-1)
- 3-((2-(4-Methoxyphenoxy)ethyl)(methyl)amino)butanenitrile (CAS 1267240-07-2)
- 2-(4-Fluoro-1H-pyrazol-1-yl)ethanol (CAS 1207961-59-8)
- 4-chloro-1-ethyl-1H-pyrazolo[3,4-d]pyrimidine (CAS 1248709-15-0)
- Potassium Trifluoro(3-iodophenyl)borate (CAS 1189097-36-6)
- 3-(3,4-Difluorophenyl)prop-2-yn-1-ol (CAS 893747-16-5)
- 2-(4-(Tert-butoxycarbonyl)piperazin-1-yl)-3-chloroisonicotinic acid (CAS 1135283-34-9)
- Semaglutide Impurity 161 (x TFA Salt) (CAS CATO-C4X-2226161)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com