Thiamphenicol CAS 15318-45-3
| CAS No. | 15318-45-3 |
| Molecular Formula | C12H15Cl2NO5S |
| Molecular Weight | 356.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies Thiamphenicol (CAS 15318-45-3), a certified reference material (molecular formula C12H15Cl2NO5S, MW 356.22 g/mol) for analytical method development and quality control.
Based on its molecular formula C12H15Cl2NO5S, Thiamphenicol contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 356.22 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), Thiamphenicol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H15Cl2NO5S |
| Molecular Weight | 356.22 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Thiamphenicol Standards
- Thiamphenicol (CAS 847-25-6)
- Thiamphenicol Impurity 2 (CAS 19934-71-5)
- Thiamphenicol Impurity 4 (CAS 27348-52-3)
- Thiamphenicol Impurity 6 (CAS 21079-44-7)
- Thiamphenicol-Methyl-D3 (CAS CATO-CCAD300798)
- ent-Thiamphenicol-d3 (CAS 1217723-41-5)
- Thiamphenicol Impurity 10 (CAS 126813-11-4)
- Thiamphenicol Impurity 9 (CAS 126429-09-2)
Recommended Standards
- Dotinurad Impurity 4 (CAS 1285573-47-8)
- 2,4-Dichloro-5-methyl-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine (CAS 1116240-03-9)
- Dotinurad Impurity 221 (CAS CATO-C4X-2494221)
- Ethyl 4-((benzyloxy)methyl)-2-bromothiazole-5-carboxylate (CAS 1206908-00-0)
- (R)-2,2,2-trifluoro-1-(3-fluorophenyl)ethanamine (CAS 1187928-53-5)
- 1-(4-Chlorophenyl)-3,4-dimethyl-1h-pyrazol-5-amine (CAS 1247184-36-6)
- N-(4-chlorophenyl)-2-methylimidazo[1,2-a]pyridine-3-carboxamide (CAS 477852-38-3)
- 3-((3-Fluorobenzyl)oxy)-5-nitro-1H-indazole (CAS 1365961-00-7)
- (S)-6-(Trifluoromethyl)chroman-4-amine (CAS 1228570-12-4)
- 2-Fluoropalmitic acid (CAS 89270-22-4)
- 52168-52-2 2-(~2~H_3_)Methyl-2-nitro(~2~H_6_)propane DTXSID50491429 (CAS 52168-52-2)
- 4-Amino-2-(methylthio)thiazole-5-carboxylic acid (CAS 94507-74-1)
- 2,6-diamino-1,4-dihydroquinazolin-4-one (CAS 53745-23-6)
- Peptide Impurity 70 TFA Salt (CAS CATO-CPTD788570)
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