Thiamphenicol Impurity 2 CAS 19934-71-5
| CAS No. | 19934-71-5 |
| Molecular Formula | C12H15Cl2NO5S |
| Molecular Weight | 356.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Thiamphenicol Impurity 2 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Thiamphenicol Impurity 2 (CAS 19934-71-5), a pharmacopoeial impurity reference standard (molecular formula C12H15Cl2NO5S, MW 356.22 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C12H15Cl2NO5S, Thiamphenicol Impurity 2 contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 356.22 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C12H15Cl2NO5S |
| Molecular Weight | 356.22 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Thiamphenicol Standards
- Thiamphenicol (CAS 847-25-6)
- Thiamphenicol Impurity 4 (CAS 27348-52-3)
- Thiamphenicol Impurity 6 (CAS 21079-44-7)
- Thiamphenicol (CAS 15318-45-3)
- Thiamphenicol-Methyl-D3 (CAS CATO-CCAD300798)
- ent-Thiamphenicol-d3 (CAS 1217723-41-5)
- Thiamphenicol Impurity 10 (CAS 126813-11-4)
- Thiamphenicol Impurity 9 (CAS 126429-09-2)
Recommended Standards
- WP1066 (CAS 857064-38-1)
- Ethyl 4,4,4-trifluoro-3-hydroxy-2-((3-(trifluoromethyl)phenyl)diazenyl)but-2-enoate (CAS 866130-98-5)
- Dotinurad Impurity 110 (CAS 888730-54-9)
- Ethyl 1-benzyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-3-carboxylate (CAS 2388985-03-1)
- Prednisolone Impurity 20 (CAS CATO-C4X-173720)
- Etelcalcetide impurity 37 (CAS 1262781-48-5)
- Abemaciclib Impurity 76 (CAS CATO-C4X-293776)
- (4Z)-1-Phenyl-4-[(phenylamino)methylidene]-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-one (CAS 477851-28-8)
- (2R,3R)-2-(3,4-Dimethoxyphenyl)-7-methoxy-3-methyl-5-((E)-prop-1-en-1-yl)-2,3-dihydrobenzofuran (CAS 41744-39-2)
- 2-Chloro-N-(5-pentyl-[1,3,4]thiadiazol-2-yl)-acetamide (CAS 15777-49-8)
- Ethyl (4-nitrophenyl)carbamate (CAS 2621-73-0)
- N'-(4-chlorobenzoyl)-1-tosylpiperidine-4-carbohydrazide (CAS 478030-14-7)
- 3-(5-Methyl-1h-pyrazol-1-yl)propan-1-ol (CAS 1006348-60-2)
- Acetyl-Tau Peptide (273-284) amide trifluoroacetate salt (CAS 1684399-52-7)
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