Montelukast Impurity 22 CAS 1266620-74-9
| CAS No. | 1266620-74-9 |
| Molecular Formula | C35H36ClNO5S |
| Molecular Weight | 618.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Montelukast Impurity 22 (CAS 1266620-74-9, C35H36ClNO5S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Montelukast Impurity 22 (C35H36ClNO5S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Montelukast Impurity 22 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C35H36ClNO5S |
| Molecular Weight | 618.18 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Montelukast Standards
- Montelukast Sulfone (CAS 2714018-24-1)
- Montelukast Impurity 9 (CAS CATO-C4X-10319)
- Montelukast Acid Impurity Disodium Salt (CAS 213380-27-9)
- Montelukast Impurity 50 (CAS 1044705-96-5)
- Montelukast Impurity 8 (CAS CATO-C4X-10318)
- Montelukast Sodium EP Impurity G (CAS 1428448-96-7)
- cis-Montelukast Sulfoxide (CAS 1428511-42-5)
- Montelukast R-Sulfoxide (CAS 1152185-58-4)
Recommended Standards
- Dimethyl Perfluoro-1,10-decanedicarboxylate (CAS 84750-88-9)
- 2-(Perfluorodecyl)ethyl Acrylate (CAS 17741-60-5)
- (S)-Methyl (1-((4-(3-(5-chloro-2-fluoro-3-(N-(methylsulfonyl)methylsulfonamido)phenyl)-1-isopropyl-1H-pyrazol-4-yl)pyrimidin-2-yl)amino)propan-2-yl)carbamate (CAS 1269440-99-4)
- 2,2'-((((2,5-Diiodo-1,4-phenylene)bis(oxy))bis(ethane-2,1-diyl))bis(oxy))bis(tetrahydro-2H-pyran) (CAS 1956377-70-0)
- Gadoxetate Impurity 33 (CAS CATO-C4X-261833)
- Empagliflozin impurity 317 (CAS CATO-C4X-1065317)
- Evocalcet impurity 59 (CAS CATO-C4X-248559)
- 1-[4-[4-(2,4-Di-tert-pentylphenoxy)butyramido]phenyl]3-pyrrolidino-4-(1-phenyltetrazol-5-yl)thiopyrazolin-5-one (CAS 107047-27-8)
- 1-Cyclohexyl-3-methyl-1H-pyrazol-5-ol (CAS 69121-55-7)
- 2-Amino-3-(4-chloro-2-nitrophenyl)propanoic acid (CAS 56433-05-7)
- 2,6-Bis(benzyloxy)benzonitrile (CAS 94088-47-8)
- 6-Hydroxy-2-(3-nitrophenyl)quinazolin-4(3H)-one (CAS 371946-32-6)
- 81923-89-9 1-Pyrenebutyryl-coenzyme A Coenzyme A, S-1-pyrenebutanoate Coenzyme A, 1-pyrenebutyryl- 1-Pyrenebutyryl-coa (CAS 81923-89-9)
- Semaglutide impurity 51 (CAS CATO-C4X-222651)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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