Montelukast Impurity 8 CAS CATO-C4X-10318
| CAS No. | CATO-C4X-10318 |
| Molecular Formula | C35H37ClNNaO3S |
| Molecular Weight | 610.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Montelukast Impurity 8.
As a process- or degradation-related impurity, Montelukast Impurity 8 (CAS CATO-C4X-10318, C35H37ClNNaO3S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a salt form, a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, Montelukast Impurity 8 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 610.18 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Montelukast Impurity 8 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C35H37ClNNaO3S |
| Molecular Weight | 610.18 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 17.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Montelukast Standards
- Montelukast Sodium EP Impurity G (CAS 1428448-96-7)
- Montelukast Impurity 50 (CAS 1044705-96-5)
- Montelukast Acid Impurity Disodium Salt (CAS 213380-27-9)
- cis-Montelukast Sulfoxide (CAS 1428511-42-5)
- Montelukast R-Sulfoxide (CAS 1152185-58-4)
- Montelukast EP Impurity I (CAS 184763-26-6)
- Montelukast 1,2-Diol (Mixture of Diastereomers) (CAS 186352-97-6)
- Montelukast - Impurity C (sodium Salt) (CAS 909796-71-0)
Recommended Standards
- Sr 146131 (CAS 221671-61-0)
- (T-4)-[[2,2'-[(1R,2R)-1,2-Cyclohexanediylbis[(nitrilo-κN)methylidyne]]bis[4,6-bis(1,1-dimethylethyl)phenolato-κO]](2-)]zinc (CAS 351498-19-6)
- 2,2-Dimethyl-propanoic Acid [3-Chloro-2-[[[2-[(triphenylmethyl)amino]-5-thiazolyl]carbonyl]amino]phenyl]methyl Ester (CAS 910298-41-8)
- (T-4)-[[2,2'-[(1S,2S)-1,2-Cyclohexanediylbis[(nitrilo-κN)methylidyne]]bis[4,6-bis(1,1-dimethylethyl)phenolato-κO]](2-)]zinc (CAS 556053-31-7)
- Pimobendan Impurity 15 (CAS CATO-C4X-246115)
- Apalutamide Impurity 96 (CAS CATO-C4X-274996)
- Ezetimibe Impurity 17(SCH59566) (CAS 1296129-15-1)
- 3-(4-Methoxyphenyl)-4,5-dihydroisoxazole (CAS 54287-95-5)
- (3aS,4S,6aR)-4-(Hydroxymethyl)hexahydro-2H-pyrrolo[3,4-d]oxazol-2-one (CAS 863392-55-6)
- 6-Chloro-4-methoxypyridin-3-amine (CAS 1256805-54-5)
- 2,6-Dichloro-N-propylpyrimidin-4-amine (CAS 72063-77-5)
- 6-(3,4-Dimethylphenyl)-3,5-dimethylimidazo[2,1-b]thiazole-2-carboxylic acid (CAS 1181261-31-3)
- (2-(Tetrahydro-2H-pyran-3-yl)pyrimidin-5-yl)boronic acid (CAS 2225152-02-1)
- C-Peptide 2 (rat) (CAS 41594-08-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com