Probenecid Impurity 4 CAS 126865-08-5

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.126865-08-5
Molecular FormulaC9H12O3S
Molecular Weight200.25 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Probenecid Impurity 4 CAS 126865-08-5 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 200.25 g/mol gives Probenecid Impurity 4 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

As a process- or degradation-related impurity, Probenecid Impurity 4 (CAS 126865-08-5, C9H12O3S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.

Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system, Probenecid Impurity 4 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 200.25 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

As a certified reference material (CRM), Probenecid Impurity 4 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC9H12O3S
Molecular Weight200.25 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1993
Sulfur Atoms1

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