6-Bromospiro[1,2,3,4-tetrahydroquinazoline-2,1’-cyclobutane]-4-one CAS 1272756-13-4
| CAS No. | 1272756-13-4 |
| Molecular Formula | C11H11BrN2O |
| Molecular Weight | 267.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-Bromospiro[1,2,3,4-tetrahydroquinazoline-2,1’-cyclobutane]-4-one (CAS 1272756-13-4), molecular formula C11H11BrN2O and molecular weight 267.12 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C11H11BrN2O, 6-Bromospiro[1,2,3,4-tetrahydroquinazoline-2,1’-cyclobutane]-4-one contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 267.12 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-Bromospiro[1,2,3,4-tetrahydroquinazoline-2,1’-cyclobutane]-4-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H11BrN2O |
| Molecular Weight | 267.12 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Bromospiro Standards
- 5'-Bromospiro[cyclopentane-1,3'-pyrrolo[2,3-b]pyridin]-2'(1'H)-one (CAS 1428799-34-1)
- 5-Bromospiro[indoline-3,3'-pyrrolidin]-2-one (CAS 1782518-75-5)
- 6-Bromospiro[indoline-3,3'-pyrrolidin]-2-one (CAS 1782636-91-2)
- 7-Bromospiro[indoline-3,3'-pyrrolidin]-2-one (CAS 1784092-17-6)
- 4-Bromospiro[indoline-3,3'-pyrrolidin]-2-one (CAS 2089311-57-7)
- 6-Bromospiro[chromane-2,1'-cyclobutan]-4-one (CAS 934555-03-0)
- 6'-Bromospiro[cyclopropane-1,3'-isochromane]-8'-carbaldehyde (CAS 2828459-32-9)
- 7-Bromospiro[chromane-2,1'-cyclobutan]-4-one (CAS 403793-82-8)
Recommended Standards
- (1-(4-Bromobenzyl)-1h-pyrazol-4-yl)methanol (CAS 1269152-28-4)
- 3-(3-Bromophenyl)-5-isopropyl-1,2,4-oxadiazole (CAS 1315365-60-6)
- ethyl 6-bromo-3-hydroxy-5-methyl-pyrazine-2-carboxylate (CAS 1269026-22-3)
- 3-(2-Bromophenyl)-5-isopropyl-1,2,4-oxadiazole (CAS 1315367-61-3)
- 5,6-Dibromoindolin-2-one (CAS 612487-49-7)
- 6-Methoxy-N1-methylbenzene-1,2-diamine (CAS 1021915-14-9)
- 1H-pyrrolo[2,3-c]pyridine-4-carbaldehyde (CAS 1100319-30-9)
- 4-(Pyrrolidin-1-ylmethyl)-3-(p-tolyl)isoxazol-5(2H)-one (CAS 61195-08-2)
- (5-Hydroxybenzofuran-3-yl)(3-methoxyphenyl)methanone (CAS 1427020-97-0)
- 4-Amino-6-cyano-5-(trifluoromethoxy)pyridine-3-sulfonyl chloride (CAS 1804026-59-2)
- N-Boc-3-fluoroaniline (CAS 81740-18-3)
- 4-(4-Bromophenyl)-1,2,3,6-tetrahydropyridine hydrochloride (CAS 103855-00-1)
- 2-Acetylnaphthalene (CAS 93-08-3)
- Semaglutide Impurity 151 xTFA (CAS CATO-C4X-2226151)
Why CATO?
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