6-Bromospiro[indoline-3,3'-pyrrolidin]-2-one CAS 1782636-91-2
| CAS No. | 1782636-91-2 |
| Molecular Formula | C11H11BrN2O |
| Molecular Weight | 267.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Bromospiro[indoline-3,3'-pyrrolidin]-2-one.
CATO supplies 6-Bromospiro[indoline-3,3'-pyrrolidin]-2-one (CAS 1782636-91-2), a certified reference material (molecular formula C11H11BrN2O, MW 267.12 g/mol) for analytical method development and quality control.
The molecular framework of 6-Bromospiro[indoline-3,3'-pyrrolidin]-2-one (C11H11BrN2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H11BrN2O |
| Molecular Weight | 267.12 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Bromospiro Standards
- 6-Bromospiro[1,2,3,4-tetrahydroquinazoline-2,1’-cyclobutane]-4-one (CAS 1272756-13-4)
- 5'-Bromospiro[cyclopentane-1,3'-pyrrolo[2,3-b]pyridin]-2'(1'H)-one (CAS 1428799-34-1)
- 5-Bromospiro[indoline-3,3'-pyrrolidin]-2-one (CAS 1782518-75-5)
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- 4-Bromospiro[indoline-3,3'-pyrrolidin]-2-one (CAS 2089311-57-7)
- 6-Bromospiro[chromane-2,1'-cyclobutan]-4-one (CAS 934555-03-0)
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Recommended Standards
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- 1-Bromo-4-(2-fluoroethanesulfonyl)benzene (CAS 1784600-41-4)
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- 1-(1H-Benzo[d][1,2,3]triazol-1-yl)-2-(1H-indol-3-yl)ethanone (CAS 1080025-88-2)
- 8,9-dimethyl-2,3,4,5-tetrahydro-1-benzoxepin-5-one (CAS 141106-39-0)
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- 3-(Trifluoromethyl)naphtho[1,2-c]isoxazole-5-carboxylic acid (CAS 1065076-41-6)
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- 1-Isocyano-2-methoxy-2-methyl-propane (CAS 109434-22-2)
- Galanin-Like Peptide (rat) trifluoroacetate salt (CAS 245114-97-0)
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