5-Bromospiro[indoline-3,3'-pyrrolidin]-2-one CAS 1782518-75-5
| CAS No. | 1782518-75-5 |
| Molecular Formula | C11H11BrN2O |
| Molecular Weight | 267.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Bromospiro[indoline-3,3'-pyrrolidin]-2-one (CAS 1782518-75-5), molecular formula C11H11BrN2O and molecular weight 267.12 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Bromospiro[indoline-3,3'-pyrrolidin]-2-one (C11H11BrN2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Bromospiro[indoline-3,3'-pyrrolidin]-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H11BrN2O |
| Molecular Weight | 267.12 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Bromospiro Standards
- 6-Bromospiro[1,2,3,4-tetrahydroquinazoline-2,1’-cyclobutane]-4-one (CAS 1272756-13-4)
- 5'-Bromospiro[cyclopentane-1,3'-pyrrolo[2,3-b]pyridin]-2'(1'H)-one (CAS 1428799-34-1)
- 6-Bromospiro[indoline-3,3'-pyrrolidin]-2-one (CAS 1782636-91-2)
- 7-Bromospiro[indoline-3,3'-pyrrolidin]-2-one (CAS 1784092-17-6)
- 4-Bromospiro[indoline-3,3'-pyrrolidin]-2-one (CAS 2089311-57-7)
- 6-Bromospiro[chromane-2,1'-cyclobutan]-4-one (CAS 934555-03-0)
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Recommended Standards
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- 4'-Formyl-[1,1'-biphenyl]-4-sulfonic acid (CAS 765217-66-1)
- L-trans-Pyrrolidine-2,4-dicarboxylic acid (CAS 64769-66-0)
- 5-Bromo-2-methylbenzenesulfonamide (CAS 56919-16-5)
- Gemcitabine Impurity 31 (CAS 142816-70-4)
- 3-(Isoxazol-5-yl)aniline (CAS 832740-15-5)
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