6'-Bromospiro[cyclopropane-1,3'-isochromane]-8'-carbaldehyde CAS 2828459-32-9
| CAS No. | 2828459-32-9 |
| Molecular Formula | C12H11BrO2 |
| Molecular Weight | 267.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6'-Bromospiro[cyclopropane-1,3'-isochromane]-8'-carbaldehyde (CAS 2828459-32-9), molecular formula C12H11BrO2 and molecular weight 267.12 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system, 6'-Bromospiro[cyclopropane-1,3'-isochromane]-8'-carbaldehyde is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 267.12 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H11BrO2 |
| Molecular Weight | 267.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | Br-containing |
Related Bromospiro Standards
- 6-Bromospiro[1,2,3,4-tetrahydroquinazoline-2,1’-cyclobutane]-4-one (CAS 1272756-13-4)
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