4-Chloro-5-nitrothiazol-2-amine CAS 127507-89-5
| CAS No. | 127507-89-5 |
| Molecular Formula | C3H2ClN3O2S |
| Molecular Weight | 179.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, 4-Chloro-5-nitrothiazol-2-amine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 179.58 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
4-Chloro-5-nitrothiazol-2-amine (CAS 127507-89-5), molecular formula C3H2ClN3O2S and molecular weight 179.58 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Chloro-5-nitrothiazol-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C3H2ClN3O2S |
| Molecular Weight | 179.58 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 4-Chloro-3-hydroxyisothiazole-5-carboxylic acid (CAS 948292-12-4)
- 3-chloro-4,5-difluorobenzonitrile (CAS 103879-29-4)
- 2-chloro-3,4-difluorobenzonitrile (CAS 924626-68-6)
- 4-chloro-1H-pyrazolo[3,4-d]pyrimidine-3-carbonitrile (CAS 1004991-91-6)
- 5-Chloro-1H-pyrazolo[3,4-b]pyrazine-3-carbonitrile (CAS 1260671-41-7)
- 4-chloro-5-hydroxy-pyridine-2-carboxylic acid (CAS 1060804-56-9)
- 3-Chloro-1H-indole-2-carbaldehyde (CAS 110912-15-7)
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Recommended Standards
- 5-Amino-6-chloro-2,3-dicyanopyrazine (CAS 56413-96-8)
- 3-Amino-5-chloropyrazine-2,6-dicarbonitrile (CAS 40559-88-4)
- 2H-Pyrazolo[4,3-d]pyrimidine-3-carbonitrile, 5-chloro- (CAS 2092193-29-6)
- 7-Chloroindole-3-carbaldehyde (CAS 1008-07-7)
- 5-Methyl-1-(2,2,2-trifluoroethyl)-1h-1,2,3-triazole-4-carboxylic acid (CAS 1248712-59-5)
- Tetraconazole (CAS 112281-77-3)
- 3-(3-Chlorophenyl)-2',5'-dichloropropiophenone (CAS 898787-37-6)
- 2-((1R,4R)-4-methylcyclohexyl)aceticacid (CAS 7132-93-6)
- 3-amino-4-sulfanylbenzene-1-sulfonamide (CAS 65192-70-3)
- Benzyl N-[(3R,4S)-3-hydroxypiperidin-4-yl]carbamate (CAS 1638744-88-3)
- (1-(Furan-2-ylmethyl)cyclopropyl)methanamine (CAS 1464902-51-9)
- (S)-1-Boc-2-(Hydroxymethyl)piperidine (CAS 134441-93-3)
- 6-Amino-2-thioxo-1,2-dihydropyrimidine-5-carbaldehyde (CAS 105161-35-1)
- Tirzepatide Impurity 47 (CAS CATO-C4X-324047)
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